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- W199378999 abstract "Inflammatory bowel diseases are the consequence of a dysregulated mucosal immune system. The mucosal immune system consists of two arms, innate and adaptive immunity, that have been studied separately for a long time. Functional studies from in vivo models of intestinal inflammation as well as results from genome-wide association studies strongly suggest a cross-regulation of both arms. The present review will illustrate this interaction by selecting examples from innate immunity and adaptive immunity, and their direct impact on each other. Broadening our view by focusing on the cross-regulated areas of the mucosal immune system will not only facilitate our understanding of disease, but furthermore will allow identification of future therapeutic targets." @default.
- W199378999 created "2016-06-24" @default.
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- W199378999 date "2011-07-21" @default.
- W199378999 modified "2023-10-03" @default.
- W199378999 title "Innate and adaptive immunity in inflammatory bowel disease." @default.
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- W199378999 doi "https://doi.org/10.3748/wjg.v17.i27.3178" @default.
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