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- W1993801739 abstract "The need for an accurate estimate of absorbed doses within and around irradiated thorax tissues necessitates the use of carefully selected materials from which phantoms are constructed. A lung substitute is more difficult to establish mostly due to its low physical density. Although many researchers have used cork as a lung substitute, very little research data address cork's characteristics to determine which type of cork is optimal as a substitute for lung tissue.Natural cork, composition cork, rubber cork, ATOM, RANDO, and a reference lung material (ICRU-44 lung tissue) were investigated to establish comparisons of physical properties. Following the determination of the respective physical properties, the dose distributions from 6 MV photon beams in water/lung substitute/water phantoms were assessed using the Monte Carlo method. Physical and electron densities affecting the dose distributions through lung tissues in different field size conditions were investigated.The physical properties (physical density, electronic density, and effective atomic number) of the composition cork are the most similar to those of the ICRU-44 lung, and the CT number of the composition cork is very similar to that of humans aged 30-60. PDD of the composition cork and the RANDO phantom are the most comparable to that of ICRU-44 lung in 1 × 1 cm(2) field size due to the combined properties of physical density (PD) and electron density per gram (EDG) of the studied lung materials. PD and EDG affect the lung dose primarily in small field size. The effects of PD are minimal in large fields, having a more rapid lateral electron equilibrium. EDG dominates PDD pattern in lung material when large fields are applied. Combined effects of PD and EDG are nonlinear for all field sizes.The composition cork is the preferred lung substitute based on physical and dosimetric properties." @default.
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- W1993801739 date "2012-03-20" @default.
- W1993801739 modified "2023-09-26" @default.
- W1993801739 title "A Comparison of physical and dosimetric properties of lung substitute materials" @default.
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- W1993801739 doi "https://doi.org/10.1118/1.3694097" @default.
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