FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1993807760> ?p ?o ?g. }

• W1993807760 endingPage "18" @default.
• W1993807760 startingPage "8" @default.
• W1993807760 abstract "Lactic acid bacteria are claimed to have immunomodulating effects. Stimulation as well as suppression of T helper (Th)1 mediated immune responses, have been described for various strains. Experiments involving Lactobacillus casei Shirota (LcS) detected mainly enhancement of innate immune responses and promotion of Th1 mediated immune reactivity. To confirm and further investigate modulation of Th1 responses and development of autoimmune disease by LcS, the consequences of oral administration of LcS were assessed in several experiments. The effect of LcS varied between the different models. No modulation was found in the mitogen-induced cell proliferation and cytokine release assays in mesenteric lymph nodes of Wistar rats. LcS inhibited the Th1 mediated immune response in an adapted murine Local Lymph Node Assay (LLNA) in BALB/c mice, whereas experimental autoimmune encephalomyelitis (EAE) in Lewis rats was aggravated. These varying effects on Th1 responses indicate that beneficial as well as harmful effects on immune related disorders could occur after LcS consumption. Since microarray analysis is suggested to be more sensitive and predictive than functional tests, gene expression profiling was included as an alternative endpoint in the testing of immunomodulation. The detected gene expression profiles did not reflect the effects of LcS on the immune system. Microarray analysis may therefore have no more predictive value than immune function assays when investigating immunomodulation by probiotics. To gain further insight into effects of probiotics on immune function, experiments including cytokine assays and gene expression analysis combined with disease models could be useful." @default.
• W1993807760 created "2016-06-24" @default.
• W1993807760 creator A5003022174 @default.
• W1993807760 creator A5005567085 @default.
• W1993807760 creator A5016939757 @default.
• W1993807760 creator A5034364029 @default.
• W1993807760 creator A5035017897 @default.
• W1993807760 creator A5036279191 @default.
• W1993807760 creator A5047058134 @default.
• W1993807760 creator A5071796957 @default.
• W1993807760 date "2006-10-01" @default.
• W1993807760 modified "2023-10-16" @default.
• W1993807760 title "Evaluation of immunomodulation by Lactobacillus casei Shirota: Immune function, autoimmunity and gene expression" @default.
• W1993807760 cites W1611284225 @default.
• W1993807760 cites W1872790762 @default.
• W1993807760 cites W1946934775 @default.
• W1993807760 cites W1968059512 @default.
• W1993807760 cites W1968082302 @default.
• W1993807760 cites W1971857522 @default.
• W1993807760 cites W1974839164 @default.
• W1993807760 cites W1975006117 @default.
• W1993807760 cites W1976008320 @default.
• W1993807760 cites W1985018681 @default.
• W1993807760 cites W1988058829 @default.
• W1993807760 cites W1990687490 @default.
• W1993807760 cites W1990873894 @default.
• W1993807760 cites W1994031544 @default.
• W1993807760 cites W1996491273 @default.
• W1993807760 cites W1999327751 @default.
• W1993807760 cites W1999585452 @default.
• W1993807760 cites W2001271695 @default.
• W1993807760 cites W2004000367 @default.
• W1993807760 cites W2006215151 @default.
• W1993807760 cites W2010953182 @default.
• W1993807760 cites W2014765417 @default.
• W1993807760 cites W2018283002 @default.
• W1993807760 cites W2025737611 @default.
• W1993807760 cites W2031205409 @default.
• W1993807760 cites W2031446487 @default.
• W1993807760 cites W2031703405 @default.
• W1993807760 cites W2032875252 @default.
• W1993807760 cites W2036525573 @default.
• W1993807760 cites W2040540076 @default.
• W1993807760 cites W2041219756 @default.
• W1993807760 cites W2052237329 @default.
• W1993807760 cites W2054726751 @default.
• W1993807760 cites W2054865262 @default.
• W1993807760 cites W2061574098 @default.
• W1993807760 cites W2061805755 @default.
• W1993807760 cites W2063720477 @default.
• W1993807760 cites W2070052490 @default.
• W1993807760 cites W2072114342 @default.
• W1993807760 cites W2078258915 @default.
• W1993807760 cites W2078450673 @default.
• W1993807760 cites W2088530215 @default.
• W1993807760 cites W2091078540 @default.
• W1993807760 cites W2097021075 @default.
• W1993807760 cites W2098101166 @default.
• W1993807760 cites W2103904373 @default.
• W1993807760 cites W2105270270 @default.
• W1993807760 cites W2108068190 @default.
• W1993807760 cites W2114164427 @default.
• W1993807760 cites W2125720303 @default.
• W1993807760 cites W2125995862 @default.
• W1993807760 cites W2126876417 @default.
• W1993807760 cites W2130255026 @default.
• W1993807760 cites W2132526669 @default.
• W1993807760 cites W2132829999 @default.
• W1993807760 cites W2134453100 @default.
• W1993807760 cites W2136540393 @default.
• W1993807760 cites W2140689677 @default.
• W1993807760 cites W2143868536 @default.
• W1993807760 cites W2144082513 @default.
• W1993807760 cites W2144113822 @default.
• W1993807760 cites W2145683869 @default.
• W1993807760 cites W2146932682 @default.
• W1993807760 cites W2148494803 @default.
• W1993807760 cites W2152398830 @default.
• W1993807760 cites W2157886452 @default.
• W1993807760 cites W2160545265 @default.
• W1993807760 cites W2161870183 @default.
• W1993807760 cites W2166236498 @default.
• W1993807760 cites W2172219164 @default.
• W1993807760 cites W2312575430 @default.
• W1993807760 cites W2315880158 @default.
• W1993807760 cites W4254555723 @default.
• W1993807760 cites W4254996853 @default.
• W1993807760 doi "https://doi.org/10.1016/j.ijfoodmicro.2006.06.009" @default.
• W1993807760 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16875751" @default.
• W1993807760 hasPublicationYear "2006" @default.
• W1993807760 type Work @default.
• W1993807760 sameAs 1993807760 @default.
• W1993807760 citedByCount "84" @default.
• W1993807760 countsByYear W19938077602012 @default.
• W1993807760 countsByYear W19938077602013 @default.
• W1993807760 countsByYear W19938077602014 @default.
• W1993807760 countsByYear W19938077602015 @default.
• W1993807760 countsByYear W19938077602016 @default.

• next