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• W1993811570 abstract "You have accessJournal of UrologySexual Function/Dysfunction/Andrology: Evaluation1 Apr 20111543 BODY MASS INDEX PREDICTS PEAK SYSTOLIC VELOCITY IN THE CAVERNOSAL ARTERY Helen R. Levey, Soroush Rais-Bahrami, Eric Ghiraldi, Kai-wen Chuang, and Bruce R Gilbert Helen R. LeveyHelen R. Levey New Hyde Park, NY More articles by this author , Soroush Rais-BahramiSoroush Rais-Bahrami New Hyde Park, NY More articles by this author , Eric GhiraldiEric Ghiraldi New Hyde Park, NY More articles by this author , Kai-wen ChuangKai-wen Chuang New Hyde Park, NY More articles by this author , and Bruce R GilbertBruce R Gilbert New Hyde Park, NY More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2011.02.1538AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Men presenting with vasculogenic erectile dysfunction (ED) are known to be at a higher risk for developing cardiovascular disease. Studies have reported ED in association with the metabolic syndrome and as a precursor of both coronary artery and peripheral vascular disease in aging men. Body mass index (BMI) has been correlated with these conditions. The objective of this study was to evaluate the effect of BMI on penile duplex parameters in men with ED. METHODS We retrospectively reviewed the charts of 82 men presenting with ED that had failed PDE5 therapy. Men with known factors, chordee, history of pelvic trauma, current radiation/chemotherapy, or congenital abnormalities were excluded from review. BMI was calculated from height and weight measurements. Penile hemodynamics were assessed through penile duplex ultrasound following injection of a vasoactive agent. Peak systolic velocity (PSV) and end diastolic velocity (EDV) were measured while the resistive index (RI) was calculated from these values. We divided our patient population into three groups: Group 1: BMI less than 25 (Normal), Group 2: BMI between 25 and 29.9 (Overweight), Group 3: BMI 30 or greater (Obese). Unpaired, two-tailed T-tests were performed to assess variability of PSV, EDV, and RI across men in Groups 1, 2 and 3. A linear regression model was performed to assess trends. RESULTS We did not find a significant difference in the PSV of men in Group 1 when compared to the PSV in men in Group 2 and Group 3. However, when we combined Group 1 and Group 2 men together, and compared them to Group 3, we found a significant difference in PSV (p<0.05). When we compared the PSV in Group 2 to Group 3, we also found a statistically significant difference in PSV (p<0.05). A linear regression analysis demonstrated a significant inverse relationship between PSV and BMI in men presenting with ED (p<0.05). CONCLUSIONS Our results demonstrate that a BMI greater than 30 predicts significant impairment in peak systolic velocity. The inverse relationship between peak systolic velocity and BMI supports a causal relationship between BMI and vasculogenic erectile dysfunction. © 2011 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 185Issue 4SApril 2011Page: e619-e620 Advertisement Copyright & Permissions© 2011 by American Urological Association Education and Research, Inc.MetricsAuthor Information Helen R. Levey New Hyde Park, NY More articles by this author Soroush Rais-Bahrami New Hyde Park, NY More articles by this author Eric Ghiraldi New Hyde Park, NY More articles by this author Kai-wen Chuang New Hyde Park, NY More articles by this author Bruce R Gilbert New Hyde Park, NY More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ..." @default.
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• W1993811570 title "1543 BODY MASS INDEX PREDICTS PEAK SYSTOLIC VELOCITY IN THE CAVERNOSAL ARTERY" @default.
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