FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1993821358> ?p ?o ?g. }

• W1993821358 endingPage "68" @default.
• W1993821358 startingPage "56" @default.
• W1993821358 abstract "Immunolabeling of heregulin, a growth factor that enhances cell proliferation in damaged utricles, and one of its binding receptors, ErbB-2, has been briefly described in the P3 rat cochlea and utricle [Zheng et al. (1999) J. Neurocytol. 28, 901-912]. However, little is known about the distribution of heregulin and its three binding receptors in adult animals. Here we describe the immunolabeling patterns for heregulin, ErbB-2, ErbB-3 and ErB-4 in the cochlea, spiral ganglion, utricle and saccule of the adult chinchilla using confocal microscopy. Heregulin immunolabeling was intense along the apical pole of Deiters cells and Hensen cells and along the membrane of supporting cells of the utricle and saccule; light immunolabeling was present in the outer layer of the spiral prominence and cytoplasm of spiral ganglion neurons. In the cochlea, intense to moderate ErbB-2 immunolabeling was evident in the cytoplasm of pillar cells, outer hair cells (OHCs), border cells, stria vascularis and spiral ligament; moderate ErbB-2 immunolabeling was present in the cytoplasm of the hair cell and supporting cell layers of the utricle and saccule. In the cochlea, light ErbB-3 immunolabeling was present in the inner hair cells, OHCs, marginal and intermediate cell layers of the stria vascularis and spiral ganglion neurons; moderate ErbB-3 immunolabeling was present in the cytoplasm of hair cells and supporting cells of the utricle and saccule. In the cochlea, utricle and saccule, ErbB-4 immunolabeling was intense in the nuclei and light to moderate in the cytoplasm and membrane of sensory cells and supporting cells. These results suggest that heregulin acting through ErbB receptors and various receptor complexes may play an important role in cell proliferation and survival in the cochlea and vestibular system." @default.
• W1993821358 created "2016-06-24" @default.
• W1993821358 creator A5046283555 @default.
• W1993821358 creator A5051993838 @default.
• W1993821358 creator A5061966364 @default.
• W1993821358 date "2002-07-01" @default.
• W1993821358 modified "2023-10-16" @default.
• W1993821358 title "Expression of heregulin and ErbB/Her receptors in adult chinchilla cochlear and vestibular sensory epithelium" @default.
• W1993821358 cites W1480092883 @default.
• W1993821358 cites W1514463309 @default.
• W1993821358 cites W1547949514 @default.
• W1993821358 cites W1558854951 @default.
• W1993821358 cites W1560013316 @default.
• W1993821358 cites W1560135459 @default.
• W1993821358 cites W1565324080 @default.
• W1993821358 cites W1813981721 @default.
• W1993821358 cites W1820697593 @default.
• W1993821358 cites W1884408152 @default.
• W1993821358 cites W1924380893 @default.
• W1993821358 cites W1973188134 @default.
• W1993821358 cites W1974980963 @default.
• W1993821358 cites W1977929477 @default.
• W1993821358 cites W1980344230 @default.
• W1993821358 cites W1981108516 @default.
• W1993821358 cites W1982780398 @default.
• W1993821358 cites W1985074818 @default.
• W1993821358 cites W1985093030 @default.
• W1993821358 cites W1985835614 @default.
• W1993821358 cites W1987657791 @default.
• W1993821358 cites W1988401988 @default.
• W1993821358 cites W1988989322 @default.
• W1993821358 cites W1989558547 @default.
• W1993821358 cites W1990040978 @default.
• W1993821358 cites W1990923018 @default.
• W1993821358 cites W1992812889 @default.
• W1993821358 cites W1992857468 @default.
• W1993821358 cites W1994413156 @default.
• W1993821358 cites W1995048201 @default.
• W1993821358 cites W1995751918 @default.
• W1993821358 cites W1997600733 @default.
• W1993821358 cites W2006819641 @default.
• W1993821358 cites W2007055114 @default.
• W1993821358 cites W2007169486 @default.
• W1993821358 cites W2007261940 @default.
• W1993821358 cites W2007518406 @default.
• W1993821358 cites W2010999141 @default.
• W1993821358 cites W2011005933 @default.
• W1993821358 cites W2011642803 @default.
• W1993821358 cites W2016405898 @default.
• W1993821358 cites W2016852463 @default.
• W1993821358 cites W2018130449 @default.
• W1993821358 cites W2021270991 @default.
• W1993821358 cites W2024515082 @default.
• W1993821358 cites W2024609246 @default.
• W1993821358 cites W2025561101 @default.
• W1993821358 cites W2026120980 @default.
• W1993821358 cites W2026904817 @default.
• W1993821358 cites W2028916500 @default.
• W1993821358 cites W2032135913 @default.
• W1993821358 cites W2033857789 @default.
• W1993821358 cites W2040913663 @default.
• W1993821358 cites W2049614426 @default.
• W1993821358 cites W2050863281 @default.
• W1993821358 cites W2051184922 @default.
• W1993821358 cites W2052594411 @default.
• W1993821358 cites W2055125633 @default.
• W1993821358 cites W2057245241 @default.
• W1993821358 cites W2058134714 @default.
• W1993821358 cites W2066660683 @default.
• W1993821358 cites W2069713422 @default.
• W1993821358 cites W2076350323 @default.
• W1993821358 cites W2078806022 @default.
• W1993821358 cites W2080250730 @default.
• W1993821358 cites W2080396142 @default.
• W1993821358 cites W2083732032 @default.
• W1993821358 cites W2089362408 @default.
• W1993821358 cites W2095257931 @default.
• W1993821358 cites W2095871457 @default.
• W1993821358 cites W2102718676 @default.
• W1993821358 cites W2104640992 @default.
• W1993821358 cites W2112149927 @default.
• W1993821358 cites W2133267068 @default.
• W1993821358 cites W2141788881 @default.
• W1993821358 cites W2153335042 @default.
• W1993821358 cites W2171363772 @default.
• W1993821358 cites W2186244224 @default.
• W1993821358 cites W2312271005 @default.
• W1993821358 cites W2329738804 @default.
• W1993821358 cites W2344695725 @default.
• W1993821358 cites W30485879 @default.
• W1993821358 cites W36626011 @default.
• W1993821358 cites W4299835783 @default.
• W1993821358 doi "https://doi.org/10.1016/s0378-5955(02)00339-8" @default.
• W1993821358 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12121740" @default.
• W1993821358 hasPublicationYear "2002" @default.
• W1993821358 type Work @default.
• W1993821358 sameAs 1993821358 @default.
• W1993821358 citedByCount "27" @default.

• next