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- W1993840282 abstract "Sensitization and systemic contact dermatitis to dental metals are well known. Ordinarily, contact dermatitis is produced by external exposure of the skin to an allergen, but sometimes a systemically administered allergen may reach the skin through the circulatory system and produce a systemic contact dermatitis.1 Metals such as nickel and chromate are well known as allergens of systemic contact dermatitis,2 but zinc is much less common. Our patient is a 61‐year‐old male who developed a generalized eczematous eruption with general fatigue. There was no history of atopy or metal allergy. The lesions consisted of a vesicular rash and oedematous erythema (Fig. 1). There were no oral symptoms, or vesicular hand eczema to suggest a feature of metal allergy. No abnormal finding was found except for slight elevation of blood eosinophils. Skin biopsy from the left lower leg showed an intraepidermal vesicle, spongiosis, exocytosis, and lymphocyte accumulation in the upper dermis." @default.
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- W1993840282 date "2003-10-30" @default.
- W1993840282 modified "2023-09-27" @default.
- W1993840282 title "Systemic contact dermatitis to zinc in dental fillings" @default.
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- W1993840282 doi "https://doi.org/10.1046/j.1365-2230.2003.01414.x" @default.
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