FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1993856738> ?p ?o ?g. }

• W1993856738 endingPage "5086" @default.
• W1993856738 startingPage "5081" @default.
• W1993856738 abstract "Visual stimuli are known to induce various changes in the receptive field properties of adult cortical neurons, but the underlying mechanisms are not well understood. Repetitive pairing of stimuli at two orientations can induce a shift in cortical orientation tuning, with the direction and magnitude of the shift depending on the temporal order and interval between the pair. Although the temporal specificity of the effect on the order of tens of milliseconds strongly suggests spike-timing-dependent synaptic plasticity (STDP) as the underlying mechanism, it remains unclear whether the modification occurs within the cortex or at earlier stages of the visual pathway. In the present study, we examined the involvement of an intracortical mechanism in this functional modification. First, we measured interocular transfer of the shift induced by monocular conditioning. We found complete transfer of the effect at both the physiological and psychophysical levels, indicating that the modification occurs largely in the cortex. Second, we analyzed the spike timing of cortical neurons during conditioning and found it commensurate with the requirement of STDP. Finally, we compared the measured shift in orientation tuning with the prediction of a model circuit that exhibits STDP at intracortical connections. This model can account for not only the temporal specificity of the effect but also the dependence of the shift on both orientations in the conditioning pair. These results indicate that modification of intracortical connections is a key mechanism in the stimulus-timing-dependent plasticity in orientation tuning." @default.
• W1993856738 created "2016-06-24" @default.
• W1993856738 creator A5036365985 @default.
• W1993856738 creator A5044338560 @default.
• W1993856738 creator A5064875450 @default.
• W1993856738 date "2004-03-24" @default.
• W1993856738 modified "2023-09-23" @default.
• W1993856738 title "Intracortical mechanism of stimulus-timing-dependent plasticity in visual cortical orientation tuning" @default.
• W1993856738 cites W1483276925 @default.
• W1993856738 cites W1483786641 @default.
• W1993856738 cites W1486852018 @default.
• W1993856738 cites W1498038217 @default.
• W1993856738 cites W1542305729 @default.
• W1993856738 cites W1564731592 @default.
• W1993856738 cites W1589692855 @default.
• W1993856738 cites W1867287134 @default.
• W1993856738 cites W1944141667 @default.
• W1993856738 cites W1966867248 @default.
• W1993856738 cites W1973822220 @default.
• W1993856738 cites W1982785464 @default.
• W1993856738 cites W1988139867 @default.
• W1993856738 cites W1990001517 @default.
• W1993856738 cites W1991233288 @default.
• W1993856738 cites W1997824093 @default.
• W1993856738 cites W2002297694 @default.
• W1993856738 cites W2008240154 @default.
• W1993856738 cites W2010180656 @default.
• W1993856738 cites W2022036926 @default.
• W1993856738 cites W2022941364 @default.
• W1993856738 cites W2028071797 @default.
• W1993856738 cites W2030159093 @default.
• W1993856738 cites W2037010168 @default.
• W1993856738 cites W2044266503 @default.
• W1993856738 cites W2057203083 @default.
• W1993856738 cites W2058352914 @default.
• W1993856738 cites W2063067007 @default.
• W1993856738 cites W2063522425 @default.
• W1993856738 cites W2075637500 @default.
• W1993856738 cites W2075794052 @default.
• W1993856738 cites W2092436621 @default.
• W1993856738 cites W2097496187 @default.
• W1993856738 cites W2102663966 @default.
• W1993856738 cites W2103594871 @default.
• W1993856738 cites W2105071895 @default.
• W1993856738 cites W2110240734 @default.
• W1993856738 cites W2115168491 @default.
• W1993856738 cites W2116360511 @default.
• W1993856738 cites W2117010174 @default.
• W1993856738 cites W2118012081 @default.
• W1993856738 cites W2122983010 @default.
• W1993856738 cites W2125396042 @default.
• W1993856738 cites W2126020484 @default.
• W1993856738 cites W2139384331 @default.
• W1993856738 cites W2141234057 @default.
• W1993856738 cites W2142963090 @default.
• W1993856738 cites W2146830847 @default.
• W1993856738 cites W2147101007 @default.
• W1993856738 cites W2153564253 @default.
• W1993856738 cites W2156259017 @default.
• W1993856738 cites W2160510653 @default.
• W1993856738 cites W2162720865 @default.
• W1993856738 cites W2165789639 @default.
• W1993856738 cites W2175136093 @default.
• W1993856738 cites W4327849171 @default.
• W1993856738 cites W2185212694 @default.
• W1993856738 doi "https://doi.org/10.1073/pnas.0302510101" @default.
• W1993856738 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/387377" @default.
• W1993856738 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15044699" @default.
• W1993856738 hasPublicationYear "2004" @default.
• W1993856738 type Work @default.
• W1993856738 sameAs 1993856738 @default.
• W1993856738 citedByCount "54" @default.
• W1993856738 countsByYear W19938567382012 @default.
• W1993856738 countsByYear W19938567382013 @default.
• W1993856738 countsByYear W19938567382014 @default.
• W1993856738 countsByYear W19938567382015 @default.
• W1993856738 countsByYear W19938567382016 @default.
• W1993856738 countsByYear W19938567382017 @default.
• W1993856738 countsByYear W19938567382019 @default.
• W1993856738 countsByYear W19938567382020 @default.
• W1993856738 countsByYear W19938567382022 @default.
• W1993856738 countsByYear W19938567382023 @default.
• W1993856738 crossrefType "journal-article" @default.
• W1993856738 hasAuthorship W1993856738A5036365985 @default.
• W1993856738 hasAuthorship W1993856738A5044338560 @default.
• W1993856738 hasAuthorship W1993856738A5064875450 @default.
• W1993856738 hasBestOaLocation W19938567381 @default.
• W1993856738 hasConcept C121332964 @default.
• W1993856738 hasConcept C15744967 @default.
• W1993856738 hasConcept C159919123 @default.
• W1993856738 hasConcept C169760540 @default.
• W1993856738 hasConcept C170493617 @default.
• W1993856738 hasConcept C185592680 @default.
• W1993856738 hasConcept C19071747 @default.
• W1993856738 hasConcept C2779345533 @default.
• W1993856738 hasConcept C2779918689 @default.
• W1993856738 hasConcept C2983650178 @default.
• W1993856738 hasConcept C47611674 @default.

• next