Matches in SemOpenAlex for { <https://semopenalex.org/work/W1993859618> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W1993859618 endingPage "446" @default.
- W1993859618 startingPage "439" @default.
- W1993859618 abstract "To investigate the effect of inhibition of cerebral Na+, K+-ATPase on cardiovascular regulation ouabain was injected into the lateral ventricle or the posterior hypothalamus in either conscious or urethane anaesthetised, deoxycorticosterone-salt hypertensive (DOCA) and sham operated (sham) rats. Ouabain injected intracerebroventricularly produced dose dependent vasopressor responses and tachycardia in the conscious rat; the magnitude of the pressor response was consistently larger in DOCA than in sham rats. In anaesthetised rats the pressor responses were accompanied by corresponding increases in abdominal sympathetic nerve activity. Thus the magnitude of the pressor responses, tachycardia, and the increases in nerve activity was again significantly greater in DOCA than in sham rats. Intrahypothalamic injections of ouabain produced pressor responses that were accompanied by consistent increases in both heart rate and abdominal sympathetic nerve activity in anaesthetised rats. In contrast to the intracerebroventricular injections the percentage increases from baseline blood pressure were significantly greater in sham than in DOCA rats at 5 min after injection. These results indicate that the centrally induced vasopressor response to ouabain, via the periventricular or bulbospinal system or both, is increased in DOCA-salt hypertensive rats whereas the pressor mechanism via the posterior hypothalamus is suppressed in DOCA rats." @default.
- W1993859618 created "2016-06-24" @default.
- W1993859618 creator A5010150912 @default.
- W1993859618 creator A5010496747 @default.
- W1993859618 creator A5020967733 @default.
- W1993859618 creator A5025161261 @default.
- W1993859618 creator A5049007602 @default.
- W1993859618 creator A5049047321 @default.
- W1993859618 creator A5071002138 @default.
- W1993859618 date "1987-06-01" @default.
- W1993859618 modified "2023-10-16" @default.
- W1993859618 title "Centrally induced vasopressor responses to ouabain in DOCA-salt hypertensive rats" @default.
- W1993859618 doi "https://doi.org/10.1093/cvr/21.6.439" @default.
- W1993859618 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2820576" @default.
- W1993859618 hasPublicationYear "1987" @default.
- W1993859618 type Work @default.
- W1993859618 sameAs 1993859618 @default.
- W1993859618 citedByCount "4" @default.
- W1993859618 countsByYear W19938596182012 @default.
- W1993859618 crossrefType "journal-article" @default.
- W1993859618 hasAuthorship W1993859618A5010150912 @default.
- W1993859618 hasAuthorship W1993859618A5010496747 @default.
- W1993859618 hasAuthorship W1993859618A5020967733 @default.
- W1993859618 hasAuthorship W1993859618A5025161261 @default.
- W1993859618 hasAuthorship W1993859618A5049007602 @default.
- W1993859618 hasAuthorship W1993859618A5049047321 @default.
- W1993859618 hasAuthorship W1993859618A5071002138 @default.
- W1993859618 hasConcept C126322002 @default.
- W1993859618 hasConcept C134018914 @default.
- W1993859618 hasConcept C178790620 @default.
- W1993859618 hasConcept C185592680 @default.
- W1993859618 hasConcept C2777953023 @default.
- W1993859618 hasConcept C2778921608 @default.
- W1993859618 hasConcept C2779133857 @default.
- W1993859618 hasConcept C2780283014 @default.
- W1993859618 hasConcept C3019263340 @default.
- W1993859618 hasConcept C42219234 @default.
- W1993859618 hasConcept C537181965 @default.
- W1993859618 hasConcept C71924100 @default.
- W1993859618 hasConcept C84393581 @default.
- W1993859618 hasConceptScore W1993859618C126322002 @default.
- W1993859618 hasConceptScore W1993859618C134018914 @default.
- W1993859618 hasConceptScore W1993859618C178790620 @default.
- W1993859618 hasConceptScore W1993859618C185592680 @default.
- W1993859618 hasConceptScore W1993859618C2777953023 @default.
- W1993859618 hasConceptScore W1993859618C2778921608 @default.
- W1993859618 hasConceptScore W1993859618C2779133857 @default.
- W1993859618 hasConceptScore W1993859618C2780283014 @default.
- W1993859618 hasConceptScore W1993859618C3019263340 @default.
- W1993859618 hasConceptScore W1993859618C42219234 @default.
- W1993859618 hasConceptScore W1993859618C537181965 @default.
- W1993859618 hasConceptScore W1993859618C71924100 @default.
- W1993859618 hasConceptScore W1993859618C84393581 @default.
- W1993859618 hasIssue "6" @default.
- W1993859618 hasLocation W19938596181 @default.
- W1993859618 hasLocation W19938596182 @default.
- W1993859618 hasOpenAccess W1993859618 @default.
- W1993859618 hasPrimaryLocation W19938596181 @default.
- W1993859618 hasRelatedWork W2000746949 @default.
- W1993859618 hasRelatedWork W2004963932 @default.
- W1993859618 hasRelatedWork W2019938707 @default.
- W1993859618 hasRelatedWork W2031947610 @default.
- W1993859618 hasRelatedWork W2077316871 @default.
- W1993859618 hasRelatedWork W2078114646 @default.
- W1993859618 hasRelatedWork W2394584325 @default.
- W1993859618 hasRelatedWork W2414862625 @default.
- W1993859618 hasRelatedWork W2414985709 @default.
- W1993859618 hasRelatedWork W2415703681 @default.
- W1993859618 hasVolume "21" @default.
- W1993859618 isParatext "false" @default.
- W1993859618 isRetracted "false" @default.
- W1993859618 magId "1993859618" @default.
- W1993859618 workType "article" @default.