FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1993864552> ?p ?o ?g. }

• W1993864552 endingPage "818" @default.
• W1993864552 startingPage "812" @default.
• W1993864552 abstract "Despite arsenic's (As) toxic potential, arsenic trioxide (As2O3) is used as a safe and effective treatment in acute promyelocytic leukaemia. However, it is unknown whether such therapy influences the balance of other trace elements in the body. In this study, mice were treated intraperitoneally daily with 1.0 mg As2O3/kg bw for 3, 5 or 7 days. As, and seven essential and nonessential trace elements with the potential to interact with As, were measured through inductively coupled plasma-mass spectrometry in serum, heart, lung, liver, pancreas, kidney, intestine and brain. As2O3 supplementation increased As in all target tissues on day 3, thereafter reaching an almost steady state. The major findings in other elements were a sequential decrease in serum zinc (on day 7 by 64%; P<0.001), and a decrease in selenium in the pancreas on day 3 (9%; P<0.05), in the intestine on day 3 (30%; P<0.001) and finally, in the brain on days 5 (12%; P<0.05) and 7 (15%; P<0.01). Changes in magnesium, iron, copper, cadmium and mercury were minor and inconsistent. This study suggests that supplementation with other trace elements may be beneficial when As2O3 treatment regimens are used in the clinic." @default.
• W1993864552 created "2016-06-24" @default.
• W1993864552 creator A5000338637 @default.
• W1993864552 creator A5014810758 @default.
• W1993864552 creator A5080504429 @default.
• W1993864552 date "2008-09-01" @default.
• W1993864552 modified "2023-10-10" @default.
• W1993864552 title "Sequential effects of daily arsenic trioxide treatment on essential and nonessential trace elements in tissues in mice" @default.
• W1993864552 cites W1500424541 @default.
• W1993864552 cites W1577787381 @default.
• W1993864552 cites W1931891535 @default.
• W1993864552 cites W1997884110 @default.
• W1993864552 cites W2015171619 @default.
• W1993864552 cites W2034380688 @default.
• W1993864552 cites W2036571488 @default.
• W1993864552 cites W2036775383 @default.
• W1993864552 cites W2040100629 @default.
• W1993864552 cites W2043534420 @default.
• W1993864552 cites W2044230889 @default.
• W1993864552 cites W2063779355 @default.
• W1993864552 cites W2064116421 @default.
• W1993864552 cites W2071337560 @default.
• W1993864552 cites W2079756038 @default.
• W1993864552 cites W2113259374 @default.
• W1993864552 cites W2118564232 @default.
• W1993864552 cites W2125922899 @default.
• W1993864552 cites W2139062456 @default.
• W1993864552 cites W2140455544 @default.
• W1993864552 cites W2146450867 @default.
• W1993864552 cites W2153643303 @default.
• W1993864552 cites W2155311549 @default.
• W1993864552 cites W2156192286 @default.
• W1993864552 cites W2159973719 @default.
• W1993864552 cites W2162114270 @default.
• W1993864552 cites W2091929101 @default.
• W1993864552 doi "https://doi.org/10.1097/cad.0b013e32830c456b" @default.
• W1993864552 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18690093" @default.
• W1993864552 hasPublicationYear "2008" @default.
• W1993864552 type Work @default.
• W1993864552 sameAs 1993864552 @default.
• W1993864552 citedByCount "19" @default.
• W1993864552 countsByYear W19938645522012 @default.
• W1993864552 countsByYear W19938645522013 @default.
• W1993864552 countsByYear W19938645522014 @default.
• W1993864552 countsByYear W19938645522016 @default.
• W1993864552 countsByYear W19938645522017 @default.
• W1993864552 countsByYear W19938645522018 @default.
• W1993864552 countsByYear W19938645522019 @default.
• W1993864552 countsByYear W19938645522023 @default.
• W1993864552 crossrefType "journal-article" @default.
• W1993864552 hasAuthorship W1993864552A5000338637 @default.
• W1993864552 hasAuthorship W1993864552A5014810758 @default.
• W1993864552 hasAuthorship W1993864552A5080504429 @default.
• W1993864552 hasConcept C126322002 @default.
• W1993864552 hasConcept C134018914 @default.
• W1993864552 hasConcept C162356407 @default.
• W1993864552 hasConcept C165697059 @default.
• W1993864552 hasConcept C178790620 @default.
• W1993864552 hasConcept C185592680 @default.
• W1993864552 hasConcept C199360897 @default.
• W1993864552 hasConcept C2777777548 @default.
• W1993864552 hasConcept C2778764654 @default.
• W1993864552 hasConcept C2780386689 @default.
• W1993864552 hasConcept C41008148 @default.
• W1993864552 hasConcept C43617362 @default.
• W1993864552 hasConcept C502230775 @default.
• W1993864552 hasConcept C535196362 @default.
• W1993864552 hasConcept C544657597 @default.
• W1993864552 hasConcept C553756173 @default.
• W1993864552 hasConcept C55493867 @default.
• W1993864552 hasConcept C71924100 @default.
• W1993864552 hasConcept C98274493 @default.
• W1993864552 hasConceptScore W1993864552C126322002 @default.
• W1993864552 hasConceptScore W1993864552C134018914 @default.
• W1993864552 hasConceptScore W1993864552C162356407 @default.
• W1993864552 hasConceptScore W1993864552C165697059 @default.
• W1993864552 hasConceptScore W1993864552C178790620 @default.
• W1993864552 hasConceptScore W1993864552C185592680 @default.
• W1993864552 hasConceptScore W1993864552C199360897 @default.
• W1993864552 hasConceptScore W1993864552C2777777548 @default.
• W1993864552 hasConceptScore W1993864552C2778764654 @default.
• W1993864552 hasConceptScore W1993864552C2780386689 @default.
• W1993864552 hasConceptScore W1993864552C41008148 @default.
• W1993864552 hasConceptScore W1993864552C43617362 @default.
• W1993864552 hasConceptScore W1993864552C502230775 @default.
• W1993864552 hasConceptScore W1993864552C535196362 @default.
• W1993864552 hasConceptScore W1993864552C544657597 @default.
• W1993864552 hasConceptScore W1993864552C553756173 @default.
• W1993864552 hasConceptScore W1993864552C55493867 @default.
• W1993864552 hasConceptScore W1993864552C71924100 @default.
• W1993864552 hasConceptScore W1993864552C98274493 @default.
• W1993864552 hasIssue "8" @default.
• W1993864552 hasLocation W19938645521 @default.
• W1993864552 hasLocation W19938645522 @default.
• W1993864552 hasOpenAccess W1993864552 @default.
• W1993864552 hasPrimaryLocation W19938645521 @default.
• W1993864552 hasRelatedWork W138530909 @default.
• W1993864552 hasRelatedWork W1498581763 @default.

• next