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- W1993884384 abstract "Intracellular recordings were made from neurones in the myenteric and submucous plexuses of the guinea-pig ileum. All myenteric neurones that were hyperpolarized by [Met5]enkephalin (or normorphine) were also hyperpolarized by noradrenaline (or clonidine); neurones unaffected by opioids were unaffected by noradrenaline. The hyperpolarizations resulted from an increase in potassium conductance of the membrane and were blocked by the respective antagonists naloxone and idazoxan. Neurones of the submucous plexus were hyperpolarized by noradrenaline but not by normorphine. The results suggest that myenteric neurones possess both μ-opioid receptors andα2-adrenoceptors whereas submucous neurones haveα2-adrenoceptors but not μ-opioid receptors." @default.
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- W1993884384 date "1985-10-01" @default.
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- W1993884384 title "μ-Opioid receptors andα2-Adrenoceptors coexist on myenteric but not on submucous neurones" @default.
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- W1993884384 doi "https://doi.org/10.1016/0306-4522(85)90014-4" @default.
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