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- W1993909070 abstract "Saccharopine [ϵ-N-(l-glutaryl-2)-l-lysine] has been found to occur in normal, untreated mouse liver. The pool of saccharopine as well as that of α-aminoadipate become labeled shortly after the administration of l-lysine-U-14C into intact mouse. In vitro experiments using the mouse liver homogenate have shown that l-lysine is converted to saccharopine in the presence of α-ketoglutarate and NADPH, and saccharopine to α-aminoadipate in the presence of NAD+. The oxidation of α-aminoadipic-δ-semialdehyde (Δ1-piperideine-6-carboxylate), the proposed reaction product of saccharopine cleavage, to α-aminoadipate is effected by either NAD+ or NADP+." @default.
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- W1993909070 date "1971-02-01" @default.
- W1993909070 modified "2023-10-01" @default.
- W1993909070 title "The conversion of l-lysine to saccharopine and α-aminoadipate in mouse" @default.
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- W1993909070 doi "https://doi.org/10.1016/0003-9861(71)90525-x" @default.
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