FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1993949959> ?p ?o ?g. }

• W1993949959 endingPage "137" @default.
• W1993949959 startingPage "132" @default.
• W1993949959 abstract "Abstract Background Psoriasis is not only related to genetic factors but also to environmental factors. However, the combined effect of genetic and environmental factors in the development of psoriasis has still been unclear. Objective The study was to analyze the combined effect of HLA‐Cw6 and smoking on psoriasis vulgaris. Methods A hospital‐based case‐control was conducted study. One hundred seventy‐eight cases and 178 controls received this epidemiological investigation and HLA typing by polymerase chain reaction utilizing sequence‐specific primers. Results The risk of psoriasis was related to smoking, the adjusted odds ratio (OR) being 2.07 ( P < 0.01), and there is a graded positive association between the risk of psoriasis and intensity or duration of smoking. Stressful life events increased the risk of psoriasis (OR = 7.87, P < 0.01). We found the waist‐hip ratio (WHR) increased the risk of psoriasis vulgaris, and OR was 2.67 ( P < 0.01) in China. Individuals harboring the HLA‐Cw6 gene obviously increased the risk of psoriasis, OR being 9.93 ( P < 0.01) after adjusted for potential confounder factors, while the OR of psoriasis for HLA‐B57 was 2.41 ( P < 0.05). Significant combined effect between HLA‐Cw6 and HLA‐B57 for psoriasis was found (OR = 10.51, P < 0.01). A striking finding is that the risk of psoriasis for smokers with HLA‐Cw6 increased about 11‐fold than non‐smokers without HLA‐Cw6, and the risk increased some 20‐fold in individuals with HLA‐Cw6 having stressful life events compared with one without HLA‐Cw6 and stressful life events. Conclusion Our study suggested that the combined effect between HLA‐Cw6 and cigarette smoking or stressful life events may play an important role in the development of psoriasis vulgaris in Han Chinese population. Conflicts of interest None declared" @default.
• W1993949959 created "2016-06-24" @default.
• W1993949959 creator A5001699296 @default.
• W1993949959 creator A5010678589 @default.
• W1993949959 creator A5023291196 @default.
• W1993949959 creator A5027426038 @default.
• W1993949959 creator A5044919548 @default.
• W1993949959 creator A5045438428 @default.
• W1993949959 creator A5049625022 @default.
• W1993949959 creator A5054186986 @default.
• W1993949959 date "2009-01-20" @default.
• W1993949959 modified "2023-10-12" @default.
• W1993949959 title "Combined effects of<i>HLA-Cw6</i>and cigarette smoking in psoriasis vulgaris: A hospital-based case-control study in China" @default.
• W1993949959 cites W1912954791 @default.
• W1993949959 cites W1964344423 @default.
• W1993949959 cites W1964995490 @default.
• W1993949959 cites W1981924240 @default.
• W1993949959 cites W1986796394 @default.
• W1993949959 cites W1989123809 @default.
• W1993949959 cites W1991748889 @default.
• W1993949959 cites W2005576094 @default.
• W1993949959 cites W2006651440 @default.
• W1993949959 cites W2016116597 @default.
• W1993949959 cites W2027442887 @default.
• W1993949959 cites W2027941153 @default.
• W1993949959 cites W2030606689 @default.
• W1993949959 cites W2034662757 @default.
• W1993949959 cites W2043504110 @default.
• W1993949959 cites W2065290004 @default.
• W1993949959 cites W2070660521 @default.
• W1993949959 cites W2080165152 @default.
• W1993949959 cites W2082491077 @default.
• W1993949959 cites W2086884950 @default.
• W1993949959 cites W2088804269 @default.
• W1993949959 cites W2091677405 @default.
• W1993949959 cites W2091681488 @default.
• W1993949959 cites W2098701094 @default.
• W1993949959 cites W2111469026 @default.
• W1993949959 cites W2114998974 @default.
• W1993949959 cites W2117003890 @default.
• W1993949959 cites W2123289485 @default.
• W1993949959 cites W2152705381 @default.
• W1993949959 cites W2153760381 @default.
• W1993949959 cites W2154375899 @default.
• W1993949959 cites W2163504863 @default.
• W1993949959 cites W2169981229 @default.
• W1993949959 cites W2293035635 @default.
• W1993949959 cites W2414878616 @default.
• W1993949959 cites W4233561050 @default.
• W1993949959 cites W4233722063 @default.
• W1993949959 cites W4318745703 @default.
• W1993949959 cites W4376848202 @default.
• W1993949959 doi "https://doi.org/10.1111/j.1468-3083.2008.02951.x" @default.
• W1993949959 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18702622" @default.
• W1993949959 hasPublicationYear "2009" @default.
• W1993949959 type Work @default.
• W1993949959 sameAs 1993949959 @default.
• W1993949959 citedByCount "59" @default.
• W1993949959 countsByYear W19939499592012 @default.
• W1993949959 countsByYear W19939499592013 @default.
• W1993949959 countsByYear W19939499592014 @default.
• W1993949959 countsByYear W19939499592015 @default.
• W1993949959 countsByYear W19939499592016 @default.
• W1993949959 countsByYear W19939499592017 @default.
• W1993949959 countsByYear W19939499592018 @default.
• W1993949959 countsByYear W19939499592019 @default.
• W1993949959 countsByYear W19939499592020 @default.
• W1993949959 countsByYear W19939499592021 @default.
• W1993949959 countsByYear W19939499592022 @default.
• W1993949959 crossrefType "journal-article" @default.
• W1993949959 hasAuthorship W1993949959A5001699296 @default.
• W1993949959 hasAuthorship W1993949959A5010678589 @default.
• W1993949959 hasAuthorship W1993949959A5023291196 @default.
• W1993949959 hasAuthorship W1993949959A5027426038 @default.
• W1993949959 hasAuthorship W1993949959A5044919548 @default.
• W1993949959 hasAuthorship W1993949959A5045438428 @default.
• W1993949959 hasAuthorship W1993949959A5049625022 @default.
• W1993949959 hasAuthorship W1993949959A5054186986 @default.
• W1993949959 hasConcept C126322002 @default.
• W1993949959 hasConcept C146304588 @default.
• W1993949959 hasConcept C147483822 @default.
• W1993949959 hasConcept C156957248 @default.
• W1993949959 hasConcept C188280979 @default.
• W1993949959 hasConcept C203014093 @default.
• W1993949959 hasConcept C2779134260 @default.
• W1993949959 hasConcept C2780564577 @default.
• W1993949959 hasConcept C67636389 @default.
• W1993949959 hasConcept C71924100 @default.
• W1993949959 hasConcept C77350462 @default.
• W1993949959 hasConceptScore W1993949959C126322002 @default.
• W1993949959 hasConceptScore W1993949959C146304588 @default.
• W1993949959 hasConceptScore W1993949959C147483822 @default.
• W1993949959 hasConceptScore W1993949959C156957248 @default.
• W1993949959 hasConceptScore W1993949959C188280979 @default.
• W1993949959 hasConceptScore W1993949959C203014093 @default.
• W1993949959 hasConceptScore W1993949959C2779134260 @default.
• W1993949959 hasConceptScore W1993949959C2780564577 @default.
• W1993949959 hasConceptScore W1993949959C67636389 @default.

• next