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- W1993974773 abstract "Prostate cancer is currently the most common cancer among Canadian men. Due to an increase in public awareness andscreening, prostate cancer is being detected at earlier stages and in much younger men. This is raising the need for bettertreatment monitoring approaches. Optoacoustic imaging is a new technique that involves exposing tissues to pulsed lightand detecting the acoustic waves generated by the tissue. Optoacoustic images of a tumour bearing mouse and an agematchedcontrol were acquired for a 775 nm illumination using a reverse-mode imaging system. A murine model ofprostate cancer, TRAMP (transgenetic adenocarcinoma of mouse prostate), was investigated. The results show anincrease in optoacoustic signal generated by the tumour compared to that generated by the surrounding tissues with acontrast ratio of 3.5. The dimensions of the tumour in the optoacoustic image agreed with the true tumour dimensions towithin 0.5 mm. In this study we show that there are detectable changes in optoacoustic signal strength that arise fromthe presence of a tumour in the prostate, which demonstrates the potential of optoacoustic imaging for the monitoring ofprostate cancer therapy." @default.
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- W1993974773 date "2010-02-11" @default.
- W1993974773 modified "2023-10-18" @default.
- W1993974773 title "Optoacoustic imaging of an animal model of prostate cancer" @default.
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- W1993974773 doi "https://doi.org/10.1117/12.842873" @default.
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