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• W1993976044 abstract "Accurate lens capsule thickness measurements are necessary for studies investigating mechanical characteristics of the capsule. Confocal Z-axis imaging was used to measure the anterior lens capsule thickness of living intact lenses with minimal tissue manipulation. Measurements of the anterior capsule thickness is reported for the first time in young and old mice from four inbred strains, BALB/c, FVB/N, C57BL/6, and 129X1, and the outbred strain ICR. Our data demonstrates that the mouse anterior lens capsule continues to grow postnatally similar to that described in other mammals. It is also shown there is a significant difference in anterior lens capsule thickness between unrelated mouse strains, suggesting that capsule thickness is a quantitative trait shared by strains with common ancestry. Measurements, taken from other regions of FVB/N capsules revealed the anterior pole to be the thickest, followed by the equatorial region and posterior pole. In addition to mouse, anterior capsule measurements taken from intact cattle, rabbit, rat lenses, and human capsulotomy specimens correlated with the overall size of the animal." @default.
• W1993976044 created "2016-06-24" @default.
• W1993976044 creator A5010301642 @default.
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• W1993976044 date "2008-10-24" @default.
• W1993976044 modified "2023-10-18" @default.
• W1993976044 title "Contributions of Mouse Genetic Background and Age on Anterior Lens Capsule Thickness" @default.
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• W1993976044 doi "https://doi.org/10.1002/ar.20753" @default.
• W1993976044 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2699617" @default.
• W1993976044 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18951502" @default.
• W1993976044 hasPublicationYear "2008" @default.
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