FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1993997286> ?p ?o ?g. }

• W1993997286 endingPage "2418" @default.
• W1993997286 startingPage "2414" @default.
• W1993997286 abstract "In the present study, we used a functional proteomic approach to identify Annexin A1 (Anxa1) interacting proteins in the Philadelphia-positive KCL22 cell line. We focused on Anxa1 because it is one of the major proteins upregulated in imatinib-sensitive KCL22S cells versus imatinib-resistant KCL22R. Our proteomic strategy revealed 21 interactors. Bioinformatic analysis showed that most of these proteins are involved in cell death processes. Among the proteins identified, we studied the interaction of Anxa1 with two phosphatases, Shp1 and Shp2, which were recently identified as biomarkers of imatinib sensitivity in patients affected by chronic myeloid leukemia. Our data open new perspectives in the search for annexin-mediated signaling pathways and may shed light on mechanisms of resistance to imatinib that are unrelated to Bcr-Abl activity. All mass spectrometry data have been deposited in the ProteomeXchange with identifier PXD000030." @default.
• W1993997286 created "2016-06-24" @default.
• W1993997286 creator A5041331809 @default.
• W1993997286 creator A5044926937 @default.
• W1993997286 creator A5054387553 @default.
• W1993997286 creator A5055992704 @default.
• W1993997286 creator A5057084037 @default.
• W1993997286 creator A5057191136 @default.
• W1993997286 creator A5076721857 @default.
• W1993997286 date "2013-07-16" @default.
• W1993997286 modified "2023-10-14" @default.
• W1993997286 title "Identification of Annexin A1 interacting proteins in chronic myeloid leukemia KCL22 cells" @default.
• W1993997286 cites W1490418776 @default.
• W1993997286 cites W1932669647 @default.
• W1993997286 cites W1967804653 @default.
• W1993997286 cites W1974315755 @default.
• W1993997286 cites W1987840462 @default.
• W1993997286 cites W2006392093 @default.
• W1993997286 cites W2032878232 @default.
• W1993997286 cites W2035896591 @default.
• W1993997286 cites W2036085023 @default.
• W1993997286 cites W2037108126 @default.
• W1993997286 cites W2046445536 @default.
• W1993997286 cites W2056638998 @default.
• W1993997286 cites W2063933529 @default.
• W1993997286 cites W2080798710 @default.
• W1993997286 cites W2084065981 @default.
• W1993997286 cites W2090850633 @default.
• W1993997286 cites W2091286644 @default.
• W1993997286 cites W2098785293 @default.
• W1993997286 cites W2102174943 @default.
• W1993997286 cites W2128864178 @default.
• W1993997286 cites W2152648806 @default.
• W1993997286 cites W2157918066 @default.
• W1993997286 cites W2318404487 @default.
• W1993997286 doi "https://doi.org/10.1002/pmic.201200444" @default.
• W1993997286 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23754495" @default.
• W1993997286 hasPublicationYear "2013" @default.
• W1993997286 type Work @default.
• W1993997286 sameAs 1993997286 @default.
• W1993997286 citedByCount "8" @default.
• W1993997286 countsByYear W19939972862014 @default.
• W1993997286 countsByYear W19939972862015 @default.
• W1993997286 countsByYear W19939972862017 @default.
• W1993997286 countsByYear W19939972862018 @default.
• W1993997286 countsByYear W19939972862019 @default.
• W1993997286 countsByYear W19939972862021 @default.
• W1993997286 countsByYear W19939972862022 @default.
• W1993997286 crossrefType "journal-article" @default.
• W1993997286 hasAuthorship W1993997286A5041331809 @default.
• W1993997286 hasAuthorship W1993997286A5044926937 @default.
• W1993997286 hasAuthorship W1993997286A5054387553 @default.
• W1993997286 hasAuthorship W1993997286A5055992704 @default.
• W1993997286 hasAuthorship W1993997286A5057084037 @default.
• W1993997286 hasAuthorship W1993997286A5057191136 @default.
• W1993997286 hasAuthorship W1993997286A5076721857 @default.
• W1993997286 hasConcept C104317684 @default.
• W1993997286 hasConcept C1491633281 @default.
• W1993997286 hasConcept C171122931 @default.
• W1993997286 hasConcept C185592680 @default.
• W1993997286 hasConcept C203014093 @default.
• W1993997286 hasConcept C2776960273 @default.
• W1993997286 hasConcept C2777583451 @default.
• W1993997286 hasConcept C2778461978 @default.
• W1993997286 hasConcept C2778729363 @default.
• W1993997286 hasConcept C2780670749 @default.
• W1993997286 hasConcept C30345302 @default.
• W1993997286 hasConcept C46111723 @default.
• W1993997286 hasConcept C502942594 @default.
• W1993997286 hasConcept C55493867 @default.
• W1993997286 hasConcept C68246026 @default.
• W1993997286 hasConcept C70721500 @default.
• W1993997286 hasConcept C86803240 @default.
• W1993997286 hasConcept C88634738 @default.
• W1993997286 hasConceptScore W1993997286C104317684 @default.
• W1993997286 hasConceptScore W1993997286C1491633281 @default.
• W1993997286 hasConceptScore W1993997286C171122931 @default.
• W1993997286 hasConceptScore W1993997286C185592680 @default.
• W1993997286 hasConceptScore W1993997286C203014093 @default.
• W1993997286 hasConceptScore W1993997286C2776960273 @default.
• W1993997286 hasConceptScore W1993997286C2777583451 @default.
• W1993997286 hasConceptScore W1993997286C2778461978 @default.
• W1993997286 hasConceptScore W1993997286C2778729363 @default.
• W1993997286 hasConceptScore W1993997286C2780670749 @default.
• W1993997286 hasConceptScore W1993997286C30345302 @default.
• W1993997286 hasConceptScore W1993997286C46111723 @default.
• W1993997286 hasConceptScore W1993997286C502942594 @default.
• W1993997286 hasConceptScore W1993997286C55493867 @default.
• W1993997286 hasConceptScore W1993997286C68246026 @default.
• W1993997286 hasConceptScore W1993997286C70721500 @default.
• W1993997286 hasConceptScore W1993997286C86803240 @default.
• W1993997286 hasConceptScore W1993997286C88634738 @default.
• W1993997286 hasFunder F4320321781 @default.
• W1993997286 hasIssue "16" @default.
• W1993997286 hasLocation W19939972861 @default.
• W1993997286 hasLocation W19939972862 @default.
• W1993997286 hasOpenAccess W1993997286 @default.
• W1993997286 hasPrimaryLocation W19939972861 @default.

• next