FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1994037971> ?p ?o ?g. }

• W1994037971 endingPage "434" @default.
• W1994037971 startingPage "425" @default.
• W1994037971 abstract "Limited data are available on long-term, seasonal changes in testicular steroidogenic activity in nondomestic felids, primarily because of the difficulties associated with longitudinal blood sampling (e.g., handling, restraint, anesthesia). Therefore, a noninvasive approach for assessing testicular androgen production was developed using the domestic cat (Felis catus) as a model. Two adult males were injected i.m. with 4 μCi14-testosterone to determine the time course and relative proportions of androgen metabolites excreted in urine and feces. Peak urinary radioactivity was detected 13 and 19 hr postinjection and accounted for ∼8% of the total radioactivity recovered. High performance liquid chromatography (HPLC) analysis detected multiple polar urinary metabolites, none of which eluted with the 3H-testosterone reference tracer. The majority of urinary testosterone metabolites consisted of nonenzyme-hydrolyzable, water-soluble (presumably conjugated) forms. In feces, radioactivity was detected in the first sample collected at 22 hr postinjection for both males, although peak metabolite excretion in one male was not observed until 61 hr postinjection. HPLC analysis detected several fecal metabolites consisting primarily of nonhydrolyzable, water-soluble forms (84.4 ± 0.9%) with some ether-soluble forms (15.6 ± 0.9%). None of the fecal androgen metabolites were associated with free testosterone. However, one or more of the water-soluble fecal metabolites was quantifiable using a commercially available testosterone radioimmunoassay. The biological relevance of this immunoactivity was confirmed in the domestic cat; concentrations were high in adult, intact males and nondetectable in intact females and castrated males and females. In addition, fecal androgen concentrations in a male Pallas' cat (Felis manul) exhibited seasonal fluctuations that corresponded with parallel changes in serum testosterone and ejaculate quality. These data indicate that testicular steroidogenic activity can be monitored non invasively in felids, providing a potentially valuable tool for endangered felid management to: (1) assess pubertal status, (2) determine the influence of season on reproduction, and (3) diagnose possible causes of sub- or infertility. © 1996 Wiley-Liss, Inc." @default.
• W1994037971 created "2016-06-24" @default.
• W1994037971 creator A5009819587 @default.
• W1994037971 creator A5023770508 @default.
• W1994037971 creator A5062206638 @default.
• W1994037971 date "1996-01-01" @default.
• W1994037971 modified "2023-09-27" @default.
• W1994037971 title "Fecal androgen metabolite analysis for noninvasive monitoring of testicular steroidogenic activity in felids" @default.
• W1994037971 cites W152510681 @default.
• W1994037971 cites W1964090826 @default.
• W1994037971 cites W1965390432 @default.
• W1994037971 cites W1985020685 @default.
• W1994037971 cites W1991473262 @default.
• W1994037971 cites W1992674425 @default.
• W1994037971 cites W1994399004 @default.
• W1994037971 cites W2005431026 @default.
• W1994037971 cites W2018217438 @default.
• W1994037971 cites W2021929179 @default.
• W1994037971 cites W2031487457 @default.
• W1994037971 cites W2054866367 @default.
• W1994037971 cites W2066135313 @default.
• W1994037971 cites W2078260361 @default.
• W1994037971 cites W2081958183 @default.
• W1994037971 cites W2089703010 @default.
• W1994037971 cites W2089797298 @default.
• W1994037971 cites W2090578620 @default.
• W1994037971 cites W2097823062 @default.
• W1994037971 cites W2104134821 @default.
• W1994037971 cites W2109759307 @default.
• W1994037971 cites W2123638619 @default.
• W1994037971 cites W2153073801 @default.
• W1994037971 cites W2169922794 @default.
• W1994037971 cites W2188693108 @default.
• W1994037971 cites W98022136 @default.
• W1994037971 doi "https://doi.org/10.1002/(sici)1098-2361(1996)15:4<425::aid-zoo7>3.0.co;2-d" @default.
• W1994037971 hasPublicationYear "1996" @default.
• W1994037971 type Work @default.
• W1994037971 sameAs 1994037971 @default.
• W1994037971 citedByCount "54" @default.
• W1994037971 countsByYear W19940379712012 @default.
• W1994037971 countsByYear W19940379712013 @default.
• W1994037971 countsByYear W19940379712014 @default.
• W1994037971 countsByYear W19940379712015 @default.
• W1994037971 countsByYear W19940379712016 @default.
• W1994037971 countsByYear W19940379712017 @default.
• W1994037971 countsByYear W19940379712019 @default.
• W1994037971 countsByYear W19940379712020 @default.
• W1994037971 countsByYear W19940379712021 @default.
• W1994037971 crossrefType "journal-article" @default.
• W1994037971 hasAuthorship W1994037971A5009819587 @default.
• W1994037971 hasAuthorship W1994037971A5023770508 @default.
• W1994037971 hasAuthorship W1994037971A5062206638 @default.
• W1994037971 hasConcept C126322002 @default.
• W1994037971 hasConcept C134018914 @default.
• W1994037971 hasConcept C151730666 @default.
• W1994037971 hasConcept C176685330 @default.
• W1994037971 hasConcept C2777477808 @default.
• W1994037971 hasConcept C2777911890 @default.
• W1994037971 hasConcept C2779279991 @default.
• W1994037971 hasConcept C2780026642 @default.
• W1994037971 hasConcept C61716771 @default.
• W1994037971 hasConcept C71315377 @default.
• W1994037971 hasConcept C71924100 @default.
• W1994037971 hasConcept C77411442 @default.
• W1994037971 hasConcept C86803240 @default.
• W1994037971 hasConceptScore W1994037971C126322002 @default.
• W1994037971 hasConceptScore W1994037971C134018914 @default.
• W1994037971 hasConceptScore W1994037971C151730666 @default.
• W1994037971 hasConceptScore W1994037971C176685330 @default.
• W1994037971 hasConceptScore W1994037971C2777477808 @default.
• W1994037971 hasConceptScore W1994037971C2777911890 @default.
• W1994037971 hasConceptScore W1994037971C2779279991 @default.
• W1994037971 hasConceptScore W1994037971C2780026642 @default.
• W1994037971 hasConceptScore W1994037971C61716771 @default.
• W1994037971 hasConceptScore W1994037971C71315377 @default.
• W1994037971 hasConceptScore W1994037971C71924100 @default.
• W1994037971 hasConceptScore W1994037971C77411442 @default.
• W1994037971 hasConceptScore W1994037971C86803240 @default.
• W1994037971 hasIssue "4" @default.
• W1994037971 hasLocation W19940379711 @default.
• W1994037971 hasOpenAccess W1994037971 @default.
• W1994037971 hasPrimaryLocation W19940379711 @default.
• W1994037971 hasRelatedWork W1977493149 @default.
• W1994037971 hasRelatedWork W1979102595 @default.
• W1994037971 hasRelatedWork W1979452793 @default.
• W1994037971 hasRelatedWork W1981433740 @default.
• W1994037971 hasRelatedWork W1986311037 @default.
• W1994037971 hasRelatedWork W2039466440 @default.
• W1994037971 hasRelatedWork W2053247908 @default.
• W1994037971 hasRelatedWork W2083564258 @default.
• W1994037971 hasRelatedWork W2089368232 @default.
• W1994037971 hasRelatedWork W2159598174 @default.
• W1994037971 hasVolume "15" @default.
• W1994037971 isParatext "false" @default.
• W1994037971 isRetracted "false" @default.
• W1994037971 magId "1994037971" @default.
• W1994037971 workType "article" @default.