FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1994047074> ?p ?o ?g. }

• W1994047074 endingPage "692" @default.
• W1994047074 startingPage "682" @default.
• W1994047074 abstract "To determine the capability of high speed computed transmission tomography to quantitate regional wall thickening dynamics over a wide range of physiologic states, left ventricular wall thickening was studied in nine anesthetized mongrel dogs in the control state and during separate infusions of dobutamine (10 μ /kg per min) and phenylephrine (25 μ /kg per min). After an intravenous bolus of contrast medium the heart was imaged from base to apex with serial transverse images in eight short-axis cine computed tomographic planes. In each dog during each experimental condition, 50 ms scans spanning the cardiac cycle were acquired at each anatomic level. Left ventricular epicardial and endocardial boundaries were identified on end-diastolic and end-systolic images at the equatorial left ventricular planes by an objective threshold contour method validated in a series of experiments performed on ex vivo anatomic specimens. End-diastolic and end-systolic frames were automatically realigned by superposition of epicardial centers of gravity and then rotated using a cross correlation function. The left ventricular wall thickness was measured manually at 16 points around the circumference by two independent observers. For the group of dogs the average percent wall thickening was 40.5 ± 28.2% and varied among segments from 18 to 70% in the control state. After dobutamine was administered, significant increases in heart rate and cardiac output (p ≤ 0.01) were accompanied by an increase in the average wall thickening (73.6 ± 51.2%; p ≤ 0.001) in the left ventricle; the average wall thickening among segments ranged from 46 to 97%. After phenylephrine administration, significant increases in mean blood pressure and cardiac output (p ≤ 0.01) were noted along with a significant increase in average left ventricular wall thickening (60.3 ± 52.5%; p ≤ 0.001). Despite an overall increase in the percent wall thickening, no statistically significant changes in segmental contraction pattern between control and drug intervention states were observed. The wall thickness measurements were highly reproducible between the two independent readers (reliability coefficient = 0.99). Cine computed tomography-derived measurements can potentially be used for quantitative assessment of left ventricular wall thickening dynamics of a single heartbeat during acute interventions, such as the administration of drugs." @default.
• W1994047074 created "2016-06-24" @default.
• W1994047074 creator A5003537386 @default.
• W1994047074 creator A5008545974 @default.
• W1994047074 creator A5019278782 @default.
• W1994047074 creator A5036673790 @default.
• W1994047074 creator A5040358030 @default.
• W1994047074 creator A5045822362 @default.
• W1994047074 creator A5047033270 @default.
• W1994047074 creator A5076143339 @default.
• W1994047074 date "1986-09-01" @default.
• W1994047074 modified "2023-09-26" @default.
• W1994047074 title "Quantitation of regional myocardial function by cine computed tomography: Pharmacologic changes in wall thickness" @default.
• W1994047074 cites W1970756732 @default.
• W1994047074 cites W1971299600 @default.
• W1994047074 cites W1974001229 @default.
• W1994047074 cites W1989021471 @default.
• W1994047074 cites W1991141831 @default.
• W1994047074 cites W1992659770 @default.
• W1994047074 cites W1998901732 @default.
• W1994047074 cites W2000475606 @default.
• W1994047074 cites W2000905433 @default.
• W1994047074 cites W2013005734 @default.
• W1994047074 cites W2016917747 @default.
• W1994047074 cites W2021839309 @default.
• W1994047074 cites W2025058052 @default.
• W1994047074 cites W2025350857 @default.
• W1994047074 cites W2026030753 @default.
• W1994047074 cites W2027555503 @default.
• W1994047074 cites W2046329350 @default.
• W1994047074 cites W2047466728 @default.
• W1994047074 cites W2048444970 @default.
• W1994047074 cites W2054183950 @default.
• W1994047074 cites W2061821372 @default.
• W1994047074 cites W2072523507 @default.
• W1994047074 cites W2085788656 @default.
• W1994047074 cites W2086186026 @default.
• W1994047074 cites W2089817311 @default.
• W1994047074 cites W2104475665 @default.
• W1994047074 cites W2114197297 @default.
• W1994047074 cites W2118531590 @default.
• W1994047074 cites W2126593264 @default.
• W1994047074 cites W2128177147 @default.
• W1994047074 cites W2151402493 @default.
• W1994047074 cites W2168289284 @default.
• W1994047074 cites W2168823533 @default.
• W1994047074 cites W2272854088 @default.
• W1994047074 cites W2399853727 @default.
• W1994047074 cites W2419179414 @default.
• W1994047074 cites W2433211703 @default.
• W1994047074 doi "https://doi.org/10.1016/s0735-1097(86)80201-7" @default.
• W1994047074 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3745717" @default.
• W1994047074 hasPublicationYear "1986" @default.
• W1994047074 type Work @default.
• W1994047074 sameAs 1994047074 @default.
• W1994047074 citedByCount "33" @default.
• W1994047074 countsByYear W19940470742013 @default.
• W1994047074 crossrefType "journal-article" @default.
• W1994047074 hasAuthorship W1994047074A5003537386 @default.
• W1994047074 hasAuthorship W1994047074A5008545974 @default.
• W1994047074 hasAuthorship W1994047074A5019278782 @default.
• W1994047074 hasAuthorship W1994047074A5036673790 @default.
• W1994047074 hasAuthorship W1994047074A5040358030 @default.
• W1994047074 hasAuthorship W1994047074A5045822362 @default.
• W1994047074 hasAuthorship W1994047074A5047033270 @default.
• W1994047074 hasAuthorship W1994047074A5076143339 @default.
• W1994047074 hasBestOaLocation W19940470741 @default.
• W1994047074 hasConcept C105702510 @default.
• W1994047074 hasConcept C126322002 @default.
• W1994047074 hasConcept C126348684 @default.
• W1994047074 hasConcept C164705383 @default.
• W1994047074 hasConcept C178853913 @default.
• W1994047074 hasConcept C185592680 @default.
• W1994047074 hasConcept C2778921608 @default.
• W1994047074 hasConcept C2779559920 @default.
• W1994047074 hasConcept C2781185063 @default.
• W1994047074 hasConcept C2989005 @default.
• W1994047074 hasConcept C43376680 @default.
• W1994047074 hasConcept C57900726 @default.
• W1994047074 hasConcept C67139541 @default.
• W1994047074 hasConcept C71924100 @default.
• W1994047074 hasConcept C84393581 @default.
• W1994047074 hasConcept C99398487 @default.
• W1994047074 hasConceptScore W1994047074C105702510 @default.
• W1994047074 hasConceptScore W1994047074C126322002 @default.
• W1994047074 hasConceptScore W1994047074C126348684 @default.
• W1994047074 hasConceptScore W1994047074C164705383 @default.
• W1994047074 hasConceptScore W1994047074C178853913 @default.
• W1994047074 hasConceptScore W1994047074C185592680 @default.
• W1994047074 hasConceptScore W1994047074C2778921608 @default.
• W1994047074 hasConceptScore W1994047074C2779559920 @default.
• W1994047074 hasConceptScore W1994047074C2781185063 @default.
• W1994047074 hasConceptScore W1994047074C2989005 @default.
• W1994047074 hasConceptScore W1994047074C43376680 @default.
• W1994047074 hasConceptScore W1994047074C57900726 @default.
• W1994047074 hasConceptScore W1994047074C67139541 @default.
• W1994047074 hasConceptScore W1994047074C71924100 @default.
• W1994047074 hasConceptScore W1994047074C84393581 @default.

• next