Matches in SemOpenAlex for { <https://semopenalex.org/work/W1994069050> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W1994069050 endingPage "9303" @default.
- W1994069050 startingPage "9299" @default.
- W1994069050 abstract "We report on single molecule measurements of the viscoelastic properties of the polysaccharide dextran using a new approach which involves acquiring the power spectral density of the thermal noise of an atomic force microscope cantilever while holding the single molecule of interest under force-clamp conditions. The attractiveness of this approach when compared with techniques which use forced oscillations under constant loading rate conditions is that it is a near-equilibrium measure of mechanical response which provides a more relevant probe of thermally driven biomolecular dynamics. Using a simple harmonic oscillator model of the cantilever−molecule system and by subtracting the response of the free cantilever taking into account hydrodynamic effects, the effective damping ζmol and elastic constant kmol of a single molecule are obtained. The molecular elasticity measured by this new technique shows a dependence on applied force that reflects the chair−boat conformational transition of the pyranose rings of the dextran molecule which is in good agreement with values obtained directly from the gradient of a conventional constant loading rate force-extension curve. The molecular damping is also seen to follow a nontrivial dependence on loading which we suggest indicates that it is internal friction and not work done on the solvent that is the dominant dissipative process." @default.
- W1994069050 created "2016-06-24" @default.
- W1994069050 creator A5028261938 @default.
- W1994069050 creator A5051093258 @default.
- W1994069050 creator A5052385071 @default.
- W1994069050 creator A5061831288 @default.
- W1994069050 creator A5072536105 @default.
- W1994069050 creator A5074934123 @default.
- W1994069050 date "2004-09-16" @default.
- W1994069050 modified "2023-09-24" @default.
- W1994069050 title "Viscoelastic Properties of Single Polysaccharide Molecules Determined by Analysis of Thermally Driven Oscillations of an Atomic Force Microscope Cantilever" @default.
- W1994069050 cites W1569994690 @default.
- W1994069050 cites W1669551441 @default.
- W1994069050 cites W1990482396 @default.
- W1994069050 cites W2000054857 @default.
- W1994069050 cites W2007406511 @default.
- W1994069050 cites W2011630211 @default.
- W1994069050 cites W2015667791 @default.
- W1994069050 cites W2023401067 @default.
- W1994069050 cites W2033257199 @default.
- W1994069050 cites W2046262665 @default.
- W1994069050 cites W2090777935 @default.
- W1994069050 cites W2130151473 @default.
- W1994069050 cites W2162791692 @default.
- W1994069050 doi "https://doi.org/10.1021/la0486178" @default.
- W1994069050 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15461521" @default.
- W1994069050 hasPublicationYear "2004" @default.
- W1994069050 type Work @default.
- W1994069050 sameAs 1994069050 @default.
- W1994069050 citedByCount "55" @default.
- W1994069050 countsByYear W19940690502012 @default.
- W1994069050 countsByYear W19940690502013 @default.
- W1994069050 countsByYear W19940690502014 @default.
- W1994069050 countsByYear W19940690502016 @default.
- W1994069050 countsByYear W19940690502017 @default.
- W1994069050 countsByYear W19940690502019 @default.
- W1994069050 countsByYear W19940690502020 @default.
- W1994069050 countsByYear W19940690502021 @default.
- W1994069050 countsByYear W19940690502022 @default.
- W1994069050 countsByYear W19940690502023 @default.
- W1994069050 crossrefType "journal-article" @default.
- W1994069050 hasAuthorship W1994069050A5028261938 @default.
- W1994069050 hasAuthorship W1994069050A5051093258 @default.
- W1994069050 hasAuthorship W1994069050A5052385071 @default.
- W1994069050 hasAuthorship W1994069050A5061831288 @default.
- W1994069050 hasAuthorship W1994069050A5072536105 @default.
- W1994069050 hasAuthorship W1994069050A5074934123 @default.
- W1994069050 hasConcept C121332964 @default.
- W1994069050 hasConcept C121854251 @default.
- W1994069050 hasConcept C141354745 @default.
- W1994069050 hasConcept C159467904 @default.
- W1994069050 hasConcept C159985019 @default.
- W1994069050 hasConcept C178790620 @default.
- W1994069050 hasConcept C185592680 @default.
- W1994069050 hasConcept C186541917 @default.
- W1994069050 hasConcept C192562407 @default.
- W1994069050 hasConcept C32909587 @default.
- W1994069050 hasConcept C41999313 @default.
- W1994069050 hasConcept C5637370 @default.
- W1994069050 hasConcept C97355855 @default.
- W1994069050 hasConceptScore W1994069050C121332964 @default.
- W1994069050 hasConceptScore W1994069050C121854251 @default.
- W1994069050 hasConceptScore W1994069050C141354745 @default.
- W1994069050 hasConceptScore W1994069050C159467904 @default.
- W1994069050 hasConceptScore W1994069050C159985019 @default.
- W1994069050 hasConceptScore W1994069050C178790620 @default.
- W1994069050 hasConceptScore W1994069050C185592680 @default.
- W1994069050 hasConceptScore W1994069050C186541917 @default.
- W1994069050 hasConceptScore W1994069050C192562407 @default.
- W1994069050 hasConceptScore W1994069050C32909587 @default.
- W1994069050 hasConceptScore W1994069050C41999313 @default.
- W1994069050 hasConceptScore W1994069050C5637370 @default.
- W1994069050 hasConceptScore W1994069050C97355855 @default.
- W1994069050 hasIssue "21" @default.
- W1994069050 hasLocation W19940690501 @default.
- W1994069050 hasLocation W19940690502 @default.
- W1994069050 hasOpenAccess W1994069050 @default.
- W1994069050 hasPrimaryLocation W19940690501 @default.
- W1994069050 hasRelatedWork W2049302849 @default.
- W1994069050 hasRelatedWork W2099079060 @default.
- W1994069050 hasRelatedWork W2200026184 @default.
- W1994069050 hasRelatedWork W2328739369 @default.
- W1994069050 hasRelatedWork W2331873473 @default.
- W1994069050 hasRelatedWork W2411527924 @default.
- W1994069050 hasRelatedWork W2760964722 @default.
- W1994069050 hasRelatedWork W3049206439 @default.
- W1994069050 hasRelatedWork W4232143030 @default.
- W1994069050 hasRelatedWork W4321135499 @default.
- W1994069050 hasVolume "20" @default.
- W1994069050 isParatext "false" @default.
- W1994069050 isRetracted "false" @default.
- W1994069050 magId "1994069050" @default.
- W1994069050 workType "article" @default.