Matches in SemOpenAlex for { <https://semopenalex.org/work/W1994088265> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W1994088265 endingPage "2080" @default.
- W1994088265 startingPage "2074" @default.
- W1994088265 abstract "BackgroundEndocarditis represents a small proportion of cardiovascular disease but is associated with high mortality. Previous studies have reported a range of outcomes, and determinants of mortality remain poorly defined.MethodsThe goal of this retrospective study was to identify independent variables for early and late mortality in 364 consecutive patients with endocarditis over a 10-year period.ResultsThe mean age of patients was 48.2 years, 35% had a history intravenous drug use, 19.8% were reoperative, and 93% had native valve endocarditis. Fever (68%) and fatigue (36%) were the most common presenting symptoms, and congestive heart failure (52%), embolization (45%), and uncontrolled sepsis (36%) were the most common indications for surgery. Overall survival at discharge, 1, 5, and 10 years was 87%, 76%, 55%, and 31%, respectively. Survival at discharge, 5, and 10 years was 91%, 69%, and 41% for surgical patients and 85%, 60%, and 31% for medically treated patients, respectively. Surgery was associated with improved short-term and long-term survival (p < 0.0.01). Independent predictors of early death were hemodynamic instability (p = 0.013) and age older than 55 years (p < 0.025). Medical treatment (p = 0.005), age older than 55 years (p = 0.032), institution (p < 0.001), New York Heart Association functional class III or IV (p = 0.002), and hemodynamic instability (p = 0.044) were predictive of late death.ConclusionsShort-term and long-term mortality from endocarditis remains high, although surgically treated patients had improved survival. Differing outcomes from two geographically similar institutions highlight the limitations of extrapolating risk factors between disparate patient populations. Endocarditis represents a small proportion of cardiovascular disease but is associated with high mortality. Previous studies have reported a range of outcomes, and determinants of mortality remain poorly defined. The goal of this retrospective study was to identify independent variables for early and late mortality in 364 consecutive patients with endocarditis over a 10-year period. The mean age of patients was 48.2 years, 35% had a history intravenous drug use, 19.8% were reoperative, and 93% had native valve endocarditis. Fever (68%) and fatigue (36%) were the most common presenting symptoms, and congestive heart failure (52%), embolization (45%), and uncontrolled sepsis (36%) were the most common indications for surgery. Overall survival at discharge, 1, 5, and 10 years was 87%, 76%, 55%, and 31%, respectively. Survival at discharge, 5, and 10 years was 91%, 69%, and 41% for surgical patients and 85%, 60%, and 31% for medically treated patients, respectively. Surgery was associated with improved short-term and long-term survival (p < 0.0.01). Independent predictors of early death were hemodynamic instability (p = 0.013) and age older than 55 years (p < 0.025). Medical treatment (p = 0.005), age older than 55 years (p = 0.032), institution (p < 0.001), New York Heart Association functional class III or IV (p = 0.002), and hemodynamic instability (p = 0.044) were predictive of late death. Short-term and long-term mortality from endocarditis remains high, although surgically treated patients had improved survival. Differing outcomes from two geographically similar institutions highlight the limitations of extrapolating risk factors between disparate patient populations." @default.
- W1994088265 created "2016-06-24" @default.
- W1994088265 creator A5001964096 @default.
- W1994088265 creator A5008264408 @default.
- W1994088265 creator A5009816972 @default.
- W1994088265 creator A5043419471 @default.
- W1994088265 creator A5048492416 @default.
- W1994088265 date "2007-06-01" @default.
- W1994088265 modified "2023-09-26" @default.
- W1994088265 title "Treatment of Endocarditis: A Decade of Experience" @default.
- W1994088265 cites W1971072605 @default.
- W1994088265 cites W2037308228 @default.
- W1994088265 cites W2045527048 @default.
- W1994088265 cites W2058069754 @default.
- W1994088265 cites W2061453535 @default.
- W1994088265 cites W2064352366 @default.
- W1994088265 cites W2071111767 @default.
- W1994088265 cites W2085114503 @default.
- W1994088265 cites W2096009044 @default.
- W1994088265 cites W2115484374 @default.
- W1994088265 cites W2165125063 @default.
- W1994088265 doi "https://doi.org/10.1016/j.athoracsur.2007.01.051" @default.
- W1994088265 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17532400" @default.
- W1994088265 hasPublicationYear "2007" @default.
- W1994088265 type Work @default.
- W1994088265 sameAs 1994088265 @default.
- W1994088265 citedByCount "17" @default.
- W1994088265 countsByYear W19940882652012 @default.
- W1994088265 countsByYear W19940882652013 @default.
- W1994088265 countsByYear W19940882652017 @default.
- W1994088265 countsByYear W19940882652018 @default.
- W1994088265 countsByYear W19940882652021 @default.
- W1994088265 countsByYear W19940882652022 @default.
- W1994088265 crossrefType "journal-article" @default.
- W1994088265 hasAuthorship W1994088265A5001964096 @default.
- W1994088265 hasAuthorship W1994088265A5008264408 @default.
- W1994088265 hasAuthorship W1994088265A5009816972 @default.
- W1994088265 hasAuthorship W1994088265A5043419471 @default.
- W1994088265 hasAuthorship W1994088265A5048492416 @default.
- W1994088265 hasConcept C126322002 @default.
- W1994088265 hasConcept C141071460 @default.
- W1994088265 hasConcept C164705383 @default.
- W1994088265 hasConcept C167135981 @default.
- W1994088265 hasConcept C178853913 @default.
- W1994088265 hasConcept C2775872228 @default.
- W1994088265 hasConcept C2778198053 @default.
- W1994088265 hasConcept C2778384902 @default.
- W1994088265 hasConcept C2780074459 @default.
- W1994088265 hasConcept C2780176578 @default.
- W1994088265 hasConcept C71924100 @default.
- W1994088265 hasConceptScore W1994088265C126322002 @default.
- W1994088265 hasConceptScore W1994088265C141071460 @default.
- W1994088265 hasConceptScore W1994088265C164705383 @default.
- W1994088265 hasConceptScore W1994088265C167135981 @default.
- W1994088265 hasConceptScore W1994088265C178853913 @default.
- W1994088265 hasConceptScore W1994088265C2775872228 @default.
- W1994088265 hasConceptScore W1994088265C2778198053 @default.
- W1994088265 hasConceptScore W1994088265C2778384902 @default.
- W1994088265 hasConceptScore W1994088265C2780074459 @default.
- W1994088265 hasConceptScore W1994088265C2780176578 @default.
- W1994088265 hasConceptScore W1994088265C71924100 @default.
- W1994088265 hasIssue "6" @default.
- W1994088265 hasLocation W19940882651 @default.
- W1994088265 hasLocation W19940882652 @default.
- W1994088265 hasOpenAccess W1994088265 @default.
- W1994088265 hasPrimaryLocation W19940882651 @default.
- W1994088265 hasRelatedWork W163208463 @default.
- W1994088265 hasRelatedWork W1984928676 @default.
- W1994088265 hasRelatedWork W1996078599 @default.
- W1994088265 hasRelatedWork W2025988618 @default.
- W1994088265 hasRelatedWork W2035179321 @default.
- W1994088265 hasRelatedWork W2412668224 @default.
- W1994088265 hasRelatedWork W2803683905 @default.
- W1994088265 hasRelatedWork W2988969500 @default.
- W1994088265 hasRelatedWork W3143536930 @default.
- W1994088265 hasRelatedWork W4319067677 @default.
- W1994088265 hasVolume "83" @default.
- W1994088265 isParatext "false" @default.
- W1994088265 isRetracted "false" @default.
- W1994088265 magId "1994088265" @default.
- W1994088265 workType "article" @default.