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• W1994097439 abstract "The management of pain differs if pain is self limiting or persistent; for example, if pain is prolonged then treatment will be managed by a multidisciplinary team in a pain clinic. Pain is not just from physical disorders but also from combinations of physiological, pathological, emotional, psychological, cognitive, environmental, and social factors (fig 1). The keys to successful pain control are the mechanisms that initiate and maintain pain. Major advances in neurobiology, from molecular studies to imaging the cortex of the brain, show the complex integration of nerve cell activity and have generated a fundamental change in attitude and expectation about the control of pain.1 Now, the public and health professionals expect to control pain by using preventive and active strategies, including drugs and physical and psychosocial interventions.Fig 1 Biopsychosocial factors that interact and modulate the experience of painThe topics we have chosen result from discussions with all grades of staff involved in the management of acute and chronic pain and range from new drug development based on scientific evidence that may impact on future pain management to a holistic approach to patient care. Our searches focused on the key words “pain,” “systematic review,” “management,” and “neuropathic.” We searched Medline, the Cochrane Library, and Health Technology Assessments, and we scrutinised the BMJ and the National Institutes of Health websites as well as professionally based websites for pain, such as that of the International Association for the Study of Pain and scientific websites such as that of the National Academy of Sciences. We identified systematic reviews from the past three years from these sources and leading scientific papers.#### Recent developmentsA major change in pain management is a move from empirical therapies to a mechanism based approachNew drug developments are targeting specific receptor subtypesPain assessment includes qualitative sensory affective and …" @default.
• W1994097439 created "2016-06-24" @default.
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• W1994097439 date "2003-03-22" @default.
• W1994097439 modified "2023-10-16" @default.
• W1994097439 title "Recent developments: Management of pain" @default.
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• W1994097439 doi "https://doi.org/10.1136/bmj.326.7390.635" @default.
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