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- W1994103726 abstract "Synthesis of single-stranded DNA of bacteriophage M 13 is blocked by rifampicin. This inhibition is not observed in an Escherichia coli mutant possessing an RNA polymerase resistant to rifampicin. Since rifampicin stops single-strand synthesis faster than chloramphenicol, inhibition by rifampicin does not seem to result from a transcriptional block of protein synthesis, particularly in view of the long half-life of the messenger RNA for M 13. It is, therefore, concluded that the interaction of rifampicin with RNA polymerase directly affects single-strand DNA synthesis. Possible mechanisms are discussed." @default.
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- W1994103726 date "1972-06-01" @default.
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- W1994103726 title "Replication of Bacteriophage M 13: Inhibition of Single-Strand DNA Synthesis by Rifampicin" @default.
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- W1994103726 doi "https://doi.org/10.1073/pnas.69.6.1634" @default.
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