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- W1994133072 abstract "The immune responses to a number of different antigens were tested under the influence of mineral oil treatment in two strains of mice: BALB/c, which is susceptible to oncogenesis by intraperitoneal administration of oil, and C57Bl, which is resistant. A limited, but general, immunological depression was elicited by the oil treatment in the BALB/c, but not in the C57Bl, animals. Immunogenicity studies on tumors induced by mineral oil in BALB/c mice suggest that this category of neoplasms also possesses tumor-associated antigenicity. The findings are discussed in relation to the role which may be played by dysfunction of the immune response in carcinogenic action. ÉTUDE DES RÉPONSES IMMUNOLOGIQUES DES SOURIS BALB/c AU COURS DE L'INDUCTION DE TUMEURS AU MOYEN D'HUILE MINÉRALE Les réponses immunologiques à différents antigènes ont été testées après administration d'huile minérale à deux souches de souris: BALB/c, pour qui l'administration intrapéritonéale d'huile minérale est carcinogène, et C57B1 qui est une souche résistante. Une dépression immunologique générale, bien que limitée, a été obtenue par ce traitement chez les souris BALB/c, mais pas chez les C57B1. L'étude immunologique des tumeurs induites par l'huile minérale chez les souris BALB/c donne à penser que cette catégorie de néoplasmes possède aussi une antigénicité liée à la tumeur. Les auteurs exposent leurs constatations en tenant compte du rǒle éventuel d'un mauvais fonctionnement de la réponse immunologique à l'action carcinogène." @default.
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- W1994133072 date "1970-11-15" @default.
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- W1994133072 title "Studies on the immune responses of BALB/c mice during tumor induction by mineral oil" @default.
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- W1994133072 doi "https://doi.org/10.1002/ijc.2910060313" @default.
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