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- W1994133649 abstract "Freshwater (4·5 ml./kg) or seawater (1·6 ml./kg) was given intratracheally in intact dogs to simulate some aspects of drowning; coronary sinus flow was measured by thermodilution flowmeter, vascular pressures by strain-gauge, and cardiac output by dye-curve. The experiments produced prolonged depression of oxygen saturation, transient hypercapnia, and a short-lived decrease in pH. Cardiac output and coronary flow were greatly increased; the latter response could be substantially inhibited if oxygen was given to the animals. Arterial glucose, lactate, and pyruvate levels increased. The coronary sinus values were generally in correspondence. Cardiac oxygen extraction (vols. per 100 ml.) decreased but percentage oxygen extraction increased. External cardiac efficiency increased, apparently in association with a shift of myocardial metabolism to an anaerobic pathway." @default.
- W1994133649 created "2016-06-24" @default.
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- W1994133649 date "1970-10-10" @default.
- W1994133649 modified "2023-09-23" @default.
- W1994133649 title "EXPERIMENTAL DROWNING: CORONARY HAEMODYNAMICS AND MYOCARDIAL METABOLISM IN THE DOG" @default.
- W1994133649 doi "https://doi.org/10.1113/expphysiol.1970.sp002084" @default.
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