Matches in SemOpenAlex for { <https://semopenalex.org/work/W1994156988> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W1994156988 endingPage "763" @default.
- W1994156988 startingPage "760" @default.
- W1994156988 abstract "Although mivacurium is eliminated by plasma cholinesterase, previous investigations have revealed either no relationship or limited correlation between mivacurium infusion rates (IRs) and plasma cholinesterase activity.Assuming that such a relationship should exist, we used a novel approach to better demonstrate the relationship in humans. Fourteen isoflurane-anesthetized adults underwent standard neuromuscular monitoring. Mivacurium was then infused at 1.0 micro gram centered dot kg-1 centered dot min-1 until twitch tension stabilized. The IR was then adjusted, using the Hill equation, to produce approximately steady state 50% (n = 14) or 90% (n = 13) twitch depression. Using these values for IR and steady-state twitch depression, the IRs expected to produce 50% and 90% twitch depression (IR50 and IR90, respectively) were estimated by nonlinear regression. Both IR50 (r2 = 0.51, P < 0.005) and IR90 (r2 = 0.48, P < 0.01) were related to plasma cholinesterase activity; the coefficient of the Hill Equation didnot vary with plasma cholinesterase activity. We conclude that mivacurium IRs are, as expected, influenced by the activity of the enzyme responsible for its elimination. (Anesth Analg 1995;80:760-3)" @default.
- W1994156988 created "2016-06-24" @default.
- W1994156988 creator A5009901846 @default.
- W1994156988 creator A5019488981 @default.
- W1994156988 creator A5065983424 @default.
- W1994156988 creator A5069001719 @default.
- W1994156988 creator A5074961488 @default.
- W1994156988 date "1995-04-01" @default.
- W1994156988 modified "2023-10-18" @default.
- W1994156988 title "The Effect of Plasma Cholinesterase Activity on Mivacurium Infusion Rates" @default.
- W1994156988 cites W1973078583 @default.
- W1994156988 cites W1974242913 @default.
- W1994156988 cites W1992253083 @default.
- W1994156988 cites W2010381502 @default.
- W1994156988 cites W2015208085 @default.
- W1994156988 cites W2041958667 @default.
- W1994156988 cites W2100498111 @default.
- W1994156988 cites W2133549754 @default.
- W1994156988 cites W2171672279 @default.
- W1994156988 doi "https://doi.org/10.1097/00000539-199504000-00019" @default.
- W1994156988 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7893031" @default.
- W1994156988 hasPublicationYear "1995" @default.
- W1994156988 type Work @default.
- W1994156988 sameAs 1994156988 @default.
- W1994156988 citedByCount "19" @default.
- W1994156988 countsByYear W19941569882014 @default.
- W1994156988 crossrefType "journal-article" @default.
- W1994156988 hasAuthorship W1994156988A5009901846 @default.
- W1994156988 hasAuthorship W1994156988A5019488981 @default.
- W1994156988 hasAuthorship W1994156988A5065983424 @default.
- W1994156988 hasAuthorship W1994156988A5069001719 @default.
- W1994156988 hasAuthorship W1994156988A5074961488 @default.
- W1994156988 hasBestOaLocation W19941569881 @default.
- W1994156988 hasConcept C126322002 @default.
- W1994156988 hasConcept C134018914 @default.
- W1994156988 hasConcept C139719470 @default.
- W1994156988 hasConcept C162324750 @default.
- W1994156988 hasConcept C2776359302 @default.
- W1994156988 hasConcept C2776867660 @default.
- W1994156988 hasConcept C3017575891 @default.
- W1994156988 hasConcept C3020079912 @default.
- W1994156988 hasConcept C31896038 @default.
- W1994156988 hasConcept C42219234 @default.
- W1994156988 hasConcept C71924100 @default.
- W1994156988 hasConceptScore W1994156988C126322002 @default.
- W1994156988 hasConceptScore W1994156988C134018914 @default.
- W1994156988 hasConceptScore W1994156988C139719470 @default.
- W1994156988 hasConceptScore W1994156988C162324750 @default.
- W1994156988 hasConceptScore W1994156988C2776359302 @default.
- W1994156988 hasConceptScore W1994156988C2776867660 @default.
- W1994156988 hasConceptScore W1994156988C3017575891 @default.
- W1994156988 hasConceptScore W1994156988C3020079912 @default.
- W1994156988 hasConceptScore W1994156988C31896038 @default.
- W1994156988 hasConceptScore W1994156988C42219234 @default.
- W1994156988 hasConceptScore W1994156988C71924100 @default.
- W1994156988 hasIssue "4" @default.
- W1994156988 hasLocation W19941569881 @default.
- W1994156988 hasLocation W19941569882 @default.
- W1994156988 hasLocation W19941569883 @default.
- W1994156988 hasOpenAccess W1994156988 @default.
- W1994156988 hasPrimaryLocation W19941569881 @default.
- W1994156988 hasRelatedWork W1982999565 @default.
- W1994156988 hasRelatedWork W1988401639 @default.
- W1994156988 hasRelatedWork W2013015495 @default.
- W1994156988 hasRelatedWork W2024252906 @default.
- W1994156988 hasRelatedWork W2038179336 @default.
- W1994156988 hasRelatedWork W2055381634 @default.
- W1994156988 hasRelatedWork W2084621567 @default.
- W1994156988 hasRelatedWork W2376569114 @default.
- W1994156988 hasRelatedWork W2415987853 @default.
- W1994156988 hasRelatedWork W2465510639 @default.
- W1994156988 hasVolume "80" @default.
- W1994156988 isParatext "false" @default.
- W1994156988 isRetracted "false" @default.
- W1994156988 magId "1994156988" @default.
- W1994156988 workType "article" @default.