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- W1994201998 abstract "The distribution of 5'-nucleotidase activity, dopaminergic [3H]spiperone binding sites, and [3H]quinuclidinyl benzilate (QNB) binding sites in different subcellular fractions of bovine caudate nucleus has been studied. Each activity was enriched in a microsomal (P3) preparation from that tissue. The microsomal preparation was further fractionated by different techniques. First, the P3 fraction, or a sonicated P3 fraction, was fractionated on a discontinuous sucrose density gradient. Second, the P3 fraction, or a digitonin pretreated P3 fraction, was fractionated on a continuous sucrose density gradient. The results obtained demonstrate that 5'-nucleotidase activity does not cofractionate with radioligand binding activity, although no difference between the distributions of [3H]spiperone binding and [3H]QNB binding were seen. It is concluded that the two radioligand binding activities are located on nonglial membranes." @default.
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- W1994201998 date "1982-05-01" @default.
- W1994201998 modified "2023-09-23" @default.
- W1994201998 title "The Distribution of Radioligand Binding Activity and 5'-Nucleotidase Activity in Bovine Caudate Nucleus Subcellular Fractions" @default.
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- W1994201998 doi "https://doi.org/10.1111/j.1471-4159.1982.tb07912.x" @default.
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