Matches in SemOpenAlex for { <https://semopenalex.org/work/W1994221490> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W1994221490 endingPage "453" @default.
- W1994221490 startingPage "453" @default.
- W1994221490 abstract "In vivo challenge studies have recently questioned oats toxicity in coeliac disease, but in vitro studies using organ culture of treated coeliac mucosa have shown that oats prolamines are able to activate a T-cell mediated mucosal immune response in the coeliac jejunum. Recent observations in coeliac children have suggested that rectum is a suitable mucosa to test the immunogenicity of cereal proteins. Aim of our study has been to investigate rectal mucosa in patients with coeliac disease after local instillation of oats prolamines. Rectal biopsy specimens were obtained from patients with treated coeliac disease before and 6 hours after rectal challenge with a peptic tryptic digest of oats prolamines (n=5), of wheat gliadin (n=10), or of ovalbumin (n=8). An immunohistochemical analysis was carried out and CD3+ and γδ+ cells counted in the epithelium and in the lamina propria. Table In conclusion, oat prolamines instillated in the rectum of coeliac patients induce a substantial local infiltration of lymphocytes both in the epithelium and in the lamina propria. This observation indicates that oats prolamines are immunogenic for the coeliac mucosa and represents a further warning against the inclusion of oats in the diet of coeliac patients." @default.
- W1994221490 created "2016-06-24" @default.
- W1994221490 creator A5019087470 @default.
- W1994221490 creator A5024359244 @default.
- W1994221490 creator A5029061517 @default.
- W1994221490 creator A5039612952 @default.
- W1994221490 creator A5048063017 @default.
- W1994221490 creator A5057553335 @default.
- W1994221490 creator A5058344933 @default.
- W1994221490 creator A5081088896 @default.
- W1994221490 date "1997-04-01" @default.
- W1994221490 modified "2023-09-26" @default.
- W1994221490 title "OATS PROLAMINES INDUCE LYMPHOCYTIC INFILTRATION WHEN INSTILLATED IN THE COELIAC RECTAL MUCOSA" @default.
- W1994221490 doi "https://doi.org/10.1097/00005176-199704000-00023" @default.
- W1994221490 hasPublicationYear "1997" @default.
- W1994221490 type Work @default.
- W1994221490 sameAs 1994221490 @default.
- W1994221490 citedByCount "1" @default.
- W1994221490 crossrefType "journal-article" @default.
- W1994221490 hasAuthorship W1994221490A5019087470 @default.
- W1994221490 hasAuthorship W1994221490A5024359244 @default.
- W1994221490 hasAuthorship W1994221490A5029061517 @default.
- W1994221490 hasAuthorship W1994221490A5039612952 @default.
- W1994221490 hasAuthorship W1994221490A5048063017 @default.
- W1994221490 hasAuthorship W1994221490A5057553335 @default.
- W1994221490 hasAuthorship W1994221490A5058344933 @default.
- W1994221490 hasAuthorship W1994221490A5081088896 @default.
- W1994221490 hasConcept C126322002 @default.
- W1994221490 hasConcept C142724271 @default.
- W1994221490 hasConcept C2775934546 @default.
- W1994221490 hasConcept C2777310793 @default.
- W1994221490 hasConcept C2779134260 @default.
- W1994221490 hasConcept C2780349322 @default.
- W1994221490 hasConcept C2781074409 @default.
- W1994221490 hasConcept C3019368612 @default.
- W1994221490 hasConcept C529295009 @default.
- W1994221490 hasConcept C71924100 @default.
- W1994221490 hasConcept C90924648 @default.
- W1994221490 hasConceptScore W1994221490C126322002 @default.
- W1994221490 hasConceptScore W1994221490C142724271 @default.
- W1994221490 hasConceptScore W1994221490C2775934546 @default.
- W1994221490 hasConceptScore W1994221490C2777310793 @default.
- W1994221490 hasConceptScore W1994221490C2779134260 @default.
- W1994221490 hasConceptScore W1994221490C2780349322 @default.
- W1994221490 hasConceptScore W1994221490C2781074409 @default.
- W1994221490 hasConceptScore W1994221490C3019368612 @default.
- W1994221490 hasConceptScore W1994221490C529295009 @default.
- W1994221490 hasConceptScore W1994221490C71924100 @default.
- W1994221490 hasConceptScore W1994221490C90924648 @default.
- W1994221490 hasIssue "4" @default.
- W1994221490 hasLocation W19942214901 @default.
- W1994221490 hasOpenAccess W1994221490 @default.
- W1994221490 hasPrimaryLocation W19942214901 @default.
- W1994221490 hasRelatedWork W1828950173 @default.
- W1994221490 hasRelatedWork W1981139829 @default.
- W1994221490 hasRelatedWork W2007756249 @default.
- W1994221490 hasRelatedWork W2087789732 @default.
- W1994221490 hasRelatedWork W2089682666 @default.
- W1994221490 hasRelatedWork W2113202766 @default.
- W1994221490 hasRelatedWork W2158247973 @default.
- W1994221490 hasRelatedWork W2166558143 @default.
- W1994221490 hasRelatedWork W2410250000 @default.
- W1994221490 hasRelatedWork W47954748 @default.
- W1994221490 hasVolume "24" @default.
- W1994221490 isParatext "false" @default.
- W1994221490 isRetracted "false" @default.
- W1994221490 magId "1994221490" @default.
- W1994221490 workType "article" @default.