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- W1994231640 abstract "Two different approaches to synthesize oligonucleotides containing the 2 '-deoxyguanosine adducts formed by nitropyrenes are described. A direct reaction of an unmodified oligonucleotide with an activated nitropyrene derivative is a convenient biomimetic approach for generating the major adducts in DNA. A total synthetic approach, by contrast, involves several synthetic steps, including Buchwald-Hartwig Pd-catalyzed coupling, but can be used for incorporating both the major and minor adducts in DNA in high yield." @default.
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- W1994231640 date "2009-03-11" @default.
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- W1994231640 title "Synthesis of Oligonucleotides Containing 2′-Deoxyguanosine Adducts of Nitropyrenes" @default.
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- W1994231640 doi "https://doi.org/10.1080/15257770902736426" @default.
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