FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1994233249> ?p ?o ?g. }

• W1994233249 endingPage "1651" @default.
• W1994233249 startingPage "1644" @default.
• W1994233249 abstract "Objective: To quantify polyneuropathy impairments and comorbidities utilizing the Rochester Epidemiology Project (2010 census = 148,201). Methods: ICD-9-CM coding identified polyneuropathy cases (2006–2010) and their 5:1 age- and sex-matched controls. Mortality and impairments were evaluated while identifying and adjusting for Charlson Index comorbidities. Results: Overall prevalence of polyneuropathy was 1.66%, and markedly rose to 6.6% in persons older than 60 years. Cases (n = 2,892) had more comorbidities than controls (n = 14,435) with higher median Charlson Index (6 vs 3, p < 0.001). Diabetes with end-organ disease represented the largest increased comorbidity in cases compared with controls (46.8% vs 6.5%). Diabetic polyneuropathy was the most common specific subtype (38.2%). Miscoded idiopathic cases and false-negative controls also commonly had diabetic polyneuropathy. Median modified Rankin Scale score was considerably higher for cases than controls (4 vs 1, p < 0.001). Multiple comorbidities were found associated with polyneuropathy after adjusting for diabetes co-occurrence, including pulmonary disease, dementia, and others. Polyneuropathy was an independent contributor to multiple functional impairments including difficulty walking (odds ratio [OR] = 1.9), climbing stairs (OR = 2.0), using an assistive device (OR = 2.0), fall tendency (OR = 2.4), work disability (OR = 4.2), lower limb amputations (OR = 3.9), and opioid use (OR = 2.7). Prevalent cases had a younger median age at death than controls (80 vs 86 years, p < 0.001), and incident cases had a 6-month shorter survival. Conclusions: Polyneuropathies have notable neurologic impairments beyond their identified multiple comorbidities. Life expectancy is shortened. Diabetic polyneuropathy is underidentified. The quantified extent of the disease burden and refined comorbidity associations emphasize that greater research efforts and health care initiatives are needed. ADL= : activities of daily living; CI= : confidence interval; CPT= : current procedural terminology; ICD-9-CM = : International Classification of Diseases, Ninth Revision, Clinical Modification ; IQR= : interquartile range; mRS= : modified Rankin Scale; OR= : odds ratio; REP= : Rochester Epidemiology Project" @default.
• W1994233249 created "2016-06-24" @default.
• W1994233249 creator A5005132437 @default.
• W1994233249 creator A5012649679 @default.
• W1994233249 creator A5044578359 @default.
• W1994233249 creator A5073303043 @default.
• W1994233249 creator A5077668464 @default.
• W1994233249 creator A5084777911 @default.
• W1994233249 date "2015-04-01" @default.
• W1994233249 modified "2023-10-01" @default.
• W1994233249 title "Impairments and comorbidities of polyneuropathy revealed by population-based analyses" @default.
• W1994233249 cites W156595675 @default.
• W1994233249 cites W1969661146 @default.
• W1994233249 cites W1977865619 @default.
• W1994233249 cites W1993105411 @default.
• W1994233249 cites W1996347667 @default.
• W1994233249 cites W2000445173 @default.
• W1994233249 cites W2002045499 @default.
• W1994233249 cites W2015216824 @default.
• W1994233249 cites W2020578652 @default.
• W1994233249 cites W2020848910 @default.
• W1994233249 cites W2034132636 @default.
• W1994233249 cites W2046859247 @default.
• W1994233249 cites W2047650782 @default.
• W1994233249 cites W2062940009 @default.
• W1994233249 cites W2075158192 @default.
• W1994233249 cites W2086753880 @default.
• W1994233249 cites W2086941566 @default.
• W1994233249 cites W2095072170 @default.
• W1994233249 cites W2101308677 @default.
• W1994233249 cites W2101697605 @default.
• W1994233249 cites W2110703451 @default.
• W1994233249 cites W2115110594 @default.
• W1994233249 cites W2124788738 @default.
• W1994233249 cites W2137393443 @default.
• W1994233249 cites W2139179143 @default.
• W1994233249 cites W2150141961 @default.
• W1994233249 cites W2152654300 @default.
• W1994233249 cites W2159452600 @default.
• W1994233249 cites W2161662405 @default.
• W1994233249 cites W2167102255 @default.
• W1994233249 cites W2774895312 @default.
• W1994233249 cites W4238374426 @default.
• W1994233249 doi "https://doi.org/10.1212/wnl.0000000000001492" @default.
• W1994233249 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4409579" @default.
• W1994233249 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25832668" @default.
• W1994233249 hasPublicationYear "2015" @default.
• W1994233249 type Work @default.
• W1994233249 sameAs 1994233249 @default.
• W1994233249 citedByCount "74" @default.
• W1994233249 countsByYear W19942332492016 @default.
• W1994233249 countsByYear W19942332492017 @default.
• W1994233249 countsByYear W19942332492018 @default.
• W1994233249 countsByYear W19942332492019 @default.
• W1994233249 countsByYear W19942332492020 @default.
• W1994233249 countsByYear W19942332492021 @default.
• W1994233249 countsByYear W19942332492022 @default.
• W1994233249 countsByYear W19942332492023 @default.
• W1994233249 crossrefType "journal-article" @default.
• W1994233249 hasAuthorship W1994233249A5005132437 @default.
• W1994233249 hasAuthorship W1994233249A5012649679 @default.
• W1994233249 hasAuthorship W1994233249A5044578359 @default.
• W1994233249 hasAuthorship W1994233249A5073303043 @default.
• W1994233249 hasAuthorship W1994233249A5077668464 @default.
• W1994233249 hasAuthorship W1994233249A5084777911 @default.
• W1994233249 hasBestOaLocation W19942332492 @default.
• W1994233249 hasConcept C107130276 @default.
• W1994233249 hasConcept C126322002 @default.
• W1994233249 hasConcept C134018914 @default.
• W1994233249 hasConcept C156957248 @default.
• W1994233249 hasConcept C1862650 @default.
• W1994233249 hasConcept C2775892965 @default.
• W1994233249 hasConcept C2778525166 @default.
• W1994233249 hasConcept C2779159551 @default.
• W1994233249 hasConcept C2908647359 @default.
• W1994233249 hasConcept C3018709324 @default.
• W1994233249 hasConcept C555293320 @default.
• W1994233249 hasConcept C71924100 @default.
• W1994233249 hasConcept C99454951 @default.
• W1994233249 hasConceptScore W1994233249C107130276 @default.
• W1994233249 hasConceptScore W1994233249C126322002 @default.
• W1994233249 hasConceptScore W1994233249C134018914 @default.
• W1994233249 hasConceptScore W1994233249C156957248 @default.
• W1994233249 hasConceptScore W1994233249C1862650 @default.
• W1994233249 hasConceptScore W1994233249C2775892965 @default.
• W1994233249 hasConceptScore W1994233249C2778525166 @default.
• W1994233249 hasConceptScore W1994233249C2779159551 @default.
• W1994233249 hasConceptScore W1994233249C2908647359 @default.
• W1994233249 hasConceptScore W1994233249C3018709324 @default.
• W1994233249 hasConceptScore W1994233249C555293320 @default.
• W1994233249 hasConceptScore W1994233249C71924100 @default.
• W1994233249 hasConceptScore W1994233249C99454951 @default.
• W1994233249 hasIssue "16" @default.
• W1994233249 hasLocation W19942332491 @default.
• W1994233249 hasLocation W19942332492 @default.
• W1994233249 hasLocation W19942332493 @default.
• W1994233249 hasLocation W19942332494 @default.
• W1994233249 hasOpenAccess W1994233249 @default.

• next