FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1994243957> ?p ?o ?g. }

• W1994243957 endingPage "643" @default.
• W1994243957 startingPage "643" @default.
• W1994243957 abstract "Objective To evaluate the safety, tolerance, and efficacy of adenosine in patients undergoing coronary artery bypass surgery. Summary Background Data Inadequate myocardial protection in patients undergoing coronary artery bypass surgery contributes to overall hospital morbidity and mortality. For this reason, new pharmacologic agents are under investigation to protect the regionally and globally ischemic heart. Methods In a double-blind, placebo-controlled trial, 253 patients were randomized to one of three cohorts. The treatment arms consisted of the intraoperative administration of cold blood cardioplegia, blood cardioplegia containing 500 μM adenosine, and blood cardioplegia containing 2 mM adenosine. Patients receiving adenosine cardioplegia were also given an infusion of adenosine (200 μg/kg/min) 10 minutes before and 15 minutes after removal of the aortic crossclamp. Invasive and noninvasive measurements of ventricular performance were obtained before, during, and after surgery. Results The high-dose adenosine cohort was associated with a trend toward a decrease in high-dose dopamine support and a lower incidence of myocardial infarction. A composite outcome analysis demonstrated that patients who received high-dose adenosine were less likely to experience one of five adverse events: high-dose dopamine use, epinephrine use, insertion of intraaortic balloon pump, myocardial infarction, or death. The operative mortality rate for all patients studied was 3.6% (9/253). Conclusions Adenosine treatment is safe and well tolerated and may be associated with fewer postoperative complications." @default.
• W1994243957 created "2016-06-24" @default.
• W1994243957 creator A5001987903 @default.
• W1994243957 creator A5009993025 @default.
• W1994243957 creator A5031436269 @default.
• W1994243957 creator A5033949749 @default.
• W1994243957 creator A5049818444 @default.
• W1994243957 creator A5056544915 @default.
• W1994243957 creator A5061836988 @default.
• W1994243957 creator A5063821733 @default.
• W1994243957 creator A5082151748 @default.
• W1994243957 date "1999-05-01" @default.
• W1994243957 modified "2023-10-16" @default.
• W1994243957 title "Adenosine Myocardial Protection" @default.
• W1994243957 cites W130604360 @default.
• W1994243957 cites W1968574288 @default.
• W1994243957 cites W1973828522 @default.
• W1994243957 cites W1979048870 @default.
• W1994243957 cites W1998350821 @default.
• W1994243957 cites W2005787394 @default.
• W1994243957 cites W2020141930 @default.
• W1994243957 cites W2024896479 @default.
• W1994243957 cites W2027937709 @default.
• W1994243957 cites W2046619690 @default.
• W1994243957 cites W2047042531 @default.
• W1994243957 cites W2048699477 @default.
• W1994243957 cites W2051070955 @default.
• W1994243957 cites W2071195559 @default.
• W1994243957 cites W2090767212 @default.
• W1994243957 cites W2091717038 @default.
• W1994243957 cites W2106843141 @default.
• W1994243957 cites W2108433896 @default.
• W1994243957 cites W2110146328 @default.
• W1994243957 cites W2111151040 @default.
• W1994243957 cites W2134142368 @default.
• W1994243957 cites W2159193479 @default.
• W1994243957 cites W2253037193 @default.
• W1994243957 cites W74069150 @default.
• W1994243957 doi "https://doi.org/10.1097/00000658-199905000-00006" @default.
• W1994243957 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1420808" @default.
• W1994243957 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10235522" @default.
• W1994243957 hasPublicationYear "1999" @default.
• W1994243957 type Work @default.
• W1994243957 sameAs 1994243957 @default.
• W1994243957 citedByCount "94" @default.
• W1994243957 countsByYear W19942439572012 @default.
• W1994243957 countsByYear W19942439572013 @default.
• W1994243957 countsByYear W19942439572014 @default.
• W1994243957 countsByYear W19942439572016 @default.
• W1994243957 countsByYear W19942439572017 @default.
• W1994243957 countsByYear W19942439572018 @default.
• W1994243957 countsByYear W19942439572019 @default.
• W1994243957 countsByYear W19942439572020 @default.
• W1994243957 countsByYear W19942439572022 @default.
• W1994243957 crossrefType "journal-article" @default.
• W1994243957 hasAuthorship W1994243957A5001987903 @default.
• W1994243957 hasAuthorship W1994243957A5009993025 @default.
• W1994243957 hasAuthorship W1994243957A5031436269 @default.
• W1994243957 hasAuthorship W1994243957A5033949749 @default.
• W1994243957 hasAuthorship W1994243957A5049818444 @default.
• W1994243957 hasAuthorship W1994243957A5056544915 @default.
• W1994243957 hasAuthorship W1994243957A5061836988 @default.
• W1994243957 hasAuthorship W1994243957A5063821733 @default.
• W1994243957 hasAuthorship W1994243957A5082151748 @default.
• W1994243957 hasBestOaLocation W19942439572 @default.
• W1994243957 hasConcept C126322002 @default.
• W1994243957 hasConcept C142724271 @default.
• W1994243957 hasConcept C164705383 @default.
• W1994243957 hasConcept C204787440 @default.
• W1994243957 hasConcept C27081682 @default.
• W1994243957 hasConcept C2775859304 @default.
• W1994243957 hasConcept C2775901492 @default.
• W1994243957 hasConcept C2776820930 @default.
• W1994243957 hasConcept C2776991684 @default.
• W1994243957 hasConcept C42219234 @default.
• W1994243957 hasConcept C500558357 @default.
• W1994243957 hasConcept C71924100 @default.
• W1994243957 hasConceptScore W1994243957C126322002 @default.
• W1994243957 hasConceptScore W1994243957C142724271 @default.
• W1994243957 hasConceptScore W1994243957C164705383 @default.
• W1994243957 hasConceptScore W1994243957C204787440 @default.
• W1994243957 hasConceptScore W1994243957C27081682 @default.
• W1994243957 hasConceptScore W1994243957C2775859304 @default.
• W1994243957 hasConceptScore W1994243957C2775901492 @default.
• W1994243957 hasConceptScore W1994243957C2776820930 @default.
• W1994243957 hasConceptScore W1994243957C2776991684 @default.
• W1994243957 hasConceptScore W1994243957C42219234 @default.
• W1994243957 hasConceptScore W1994243957C500558357 @default.
• W1994243957 hasConceptScore W1994243957C71924100 @default.
• W1994243957 hasIssue "5" @default.
• W1994243957 hasLocation W19942439571 @default.
• W1994243957 hasLocation W19942439572 @default.
• W1994243957 hasLocation W19942439573 @default.
• W1994243957 hasOpenAccess W1994243957 @default.
• W1994243957 hasPrimaryLocation W19942439571 @default.
• W1994243957 hasRelatedWork W1996798625 @default.
• W1994243957 hasRelatedWork W2049400617 @default.
• W1994243957 hasRelatedWork W2070218017 @default.

• next