FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1994248664> ?p ?o ?g. }

• W1994248664 endingPage "192" @default.
• W1994248664 startingPage "185" @default.
• W1994248664 abstract "Muscarinic M2, M4, and M2-M4 chimera receptors were transiently expressed in HEK-293 tsA201 cells, and agonist-dependent internalization of these receptors and recycling of internalized receptors were examined by measuring the amount of cell-surface receptors as [3H]N-methylscopolamine (NMS) binding activity. Coexpression of a dominant negative form of dynamin (DN-dynamin,dynamin K44A) greatly reduced the agonist-dependent internalization of M4 receptors but not of M2 receptors, as was reported by Vögler et al. (J Biol Chem 273, 12155-12160, 1998).The agonist-dependent internalization of M2/M4-i3/M2 chimera receptors (M2 receptors with the i3 loop replaced by that of M4 receptors) was greatly reduced by co-expression of DN-dynamin as was the case for M4 receptors, whereas the agonist-dependent internalization of M4/M2-i3/M4 chimera receptors was hardly affected by co-expression of DN-dynamin as was the case for M2 receptors.Internalized M2/M4-i3/M2 receptors as well as internalized M4 receptors were shown to be recycled back to the cell surface after removal of agonists, whereas no recycling was observed for M4/M2-i3/M4 receptors as well as M2 receptors. These results indicate that the i3 loops of M2 and M4 receptors take a major role in their agonist-dependent internalization and recycling." @default.
• W1994248664 created "2016-06-24" @default.
• W1994248664 creator A5000539432 @default.
• W1994248664 creator A5002576421 @default.
• W1994248664 creator A5006335559 @default.
• W1994248664 creator A5065554032 @default.
• W1994248664 date "2014-01-01" @default.
• W1994248664 modified "2023-09-28" @default.
• W1994248664 title "Role of the third intracellular loop in the subtype-specific internalization and recycling of muscarinic M2 and M4 receptors" @default.
• W1994248664 cites W1504684037 @default.
• W1994248664 cites W1504756577 @default.
• W1994248664 cites W1531303582 @default.
• W1994248664 cites W1594024004 @default.
• W1994248664 cites W1947826208 @default.
• W1994248664 cites W1963796740 @default.
• W1994248664 cites W1967998137 @default.
• W1994248664 cites W1980132250 @default.
• W1994248664 cites W1985759771 @default.
• W1994248664 cites W1991899689 @default.
• W1994248664 cites W1992620183 @default.
• W1994248664 cites W1994034473 @default.
• W1994248664 cites W1996699433 @default.
• W1994248664 cites W1996895789 @default.
• W1994248664 cites W2012642649 @default.
• W1994248664 cites W2032058654 @default.
• W1994248664 cites W2035293723 @default.
• W1994248664 cites W2035745394 @default.
• W1994248664 cites W2046702929 @default.
• W1994248664 cites W2052467519 @default.
• W1994248664 cites W2066918946 @default.
• W1994248664 cites W2067011931 @default.
• W1994248664 cites W2073404673 @default.
• W1994248664 cites W2078834369 @default.
• W1994248664 cites W2078867772 @default.
• W1994248664 cites W2087886422 @default.
• W1994248664 cites W2092532048 @default.
• W1994248664 cites W2094469376 @default.
• W1994248664 cites W2108696499 @default.
• W1994248664 cites W2139332405 @default.
• W1994248664 cites W2151074506 @default.
• W1994248664 cites W2153665908 @default.
• W1994248664 cites W2163352150 @default.
• W1994248664 cites W2169527010 @default.
• W1994248664 cites W2340888845 @default.
• W1994248664 cites W2553315459 @default.
• W1994248664 doi "https://doi.org/10.2220/biomedres.35.185" @default.
• W1994248664 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24942857" @default.
• W1994248664 hasPublicationYear "2014" @default.
• W1994248664 type Work @default.
• W1994248664 sameAs 1994248664 @default.
• W1994248664 citedByCount "5" @default.
• W1994248664 countsByYear W19942486642014 @default.
• W1994248664 countsByYear W19942486642018 @default.
• W1994248664 countsByYear W19942486642020 @default.
• W1994248664 countsByYear W19942486642021 @default.
• W1994248664 crossrefType "journal-article" @default.
• W1994248664 hasAuthorship W1994248664A5000539432 @default.
• W1994248664 hasAuthorship W1994248664A5002576421 @default.
• W1994248664 hasAuthorship W1994248664A5006335559 @default.
• W1994248664 hasAuthorship W1994248664A5065554032 @default.
• W1994248664 hasBestOaLocation W19942486641 @default.
• W1994248664 hasConcept C135285700 @default.
• W1994248664 hasConcept C139770010 @default.
• W1994248664 hasConcept C156407911 @default.
• W1994248664 hasConcept C170493617 @default.
• W1994248664 hasConcept C185592680 @default.
• W1994248664 hasConcept C203270574 @default.
• W1994248664 hasConcept C26702167 @default.
• W1994248664 hasConcept C2778938600 @default.
• W1994248664 hasConcept C28005876 @default.
• W1994248664 hasConcept C33789571 @default.
• W1994248664 hasConcept C42221972 @default.
• W1994248664 hasConcept C55493867 @default.
• W1994248664 hasConcept C86803240 @default.
• W1994248664 hasConcept C95444343 @default.
• W1994248664 hasConceptScore W1994248664C135285700 @default.
• W1994248664 hasConceptScore W1994248664C139770010 @default.
• W1994248664 hasConceptScore W1994248664C156407911 @default.
• W1994248664 hasConceptScore W1994248664C170493617 @default.
• W1994248664 hasConceptScore W1994248664C185592680 @default.
• W1994248664 hasConceptScore W1994248664C203270574 @default.
• W1994248664 hasConceptScore W1994248664C26702167 @default.
• W1994248664 hasConceptScore W1994248664C2778938600 @default.
• W1994248664 hasConceptScore W1994248664C28005876 @default.
• W1994248664 hasConceptScore W1994248664C33789571 @default.
• W1994248664 hasConceptScore W1994248664C42221972 @default.
• W1994248664 hasConceptScore W1994248664C55493867 @default.
• W1994248664 hasConceptScore W1994248664C86803240 @default.
• W1994248664 hasConceptScore W1994248664C95444343 @default.
• W1994248664 hasIssue "3" @default.
• W1994248664 hasLocation W19942486641 @default.
• W1994248664 hasLocation W19942486642 @default.
• W1994248664 hasOpenAccess W1994248664 @default.
• W1994248664 hasPrimaryLocation W19942486641 @default.
• W1994248664 hasRelatedWork W1994248664 @default.
• W1994248664 hasRelatedWork W2031590523 @default.
• W1994248664 hasRelatedWork W2036805010 @default.
• W1994248664 hasRelatedWork W2150339003 @default.

• next