FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1994249743> ?p ?o ?g. }

• W1994249743 endingPage "306" @default.
• W1994249743 startingPage "302" @default.
• W1994249743 abstract "Renal impairment is a frequent complication of multiple myeloma (MM) and is associated with significant morbidity and increased early death rate. Bortezomib is active and well tolerated in patients with MM who present or develop renal impairment. We analyzed 46 consecutive patients who presented with renal impairment in order to evaluate the impact of bortezomib on the improvement of renal function and to identify predictive factors associated with renal response. All patients received bortezomib with dexamethasone with or without other agents. Renal response was documented in 59% of patients within a median of 11 days (range, 8-41 days). Two of 9 patients who required dialysis became dialysis independent. A complete renal response (CRrenal) was documented in 30% of patients. Toxicities were similar to those seen in myeloma patients without renal failure who were treated with bortezomib-based regimens. Patients with light chain—only myeloma had a higher probability of achieving a renal response, and previously untreated patients had a higher probability for complete resolution of renal impairment, while light chain—only myeloma was independently associated with a shorter time to renal response. The degree of renal impairment was not predictive of the probability for renal response or CRrenal; however, in a subset of patients for whom cystatin C was available, a baseline cystatin C > 2 mg/L or cystatin C calculated estimated glomerular filtration rate < 30 mL/min were associated with a lower probability of CRrenal. We conclude that bortezomib-based regimens may improve renal function in the majority of myeloma patients with renal impairment." @default.
• W1994249743 created "2016-06-24" @default.
• W1994249743 creator A5004781025 @default.
• W1994249743 creator A5007766504 @default.
• W1994249743 creator A5018522443 @default.
• W1994249743 creator A5024471527 @default.
• W1994249743 creator A5040774907 @default.
• W1994249743 creator A5041407463 @default.
• W1994249743 creator A5046758725 @default.
• W1994249743 creator A5050531750 @default.
• W1994249743 creator A5051403132 @default.
• W1994249743 creator A5057736578 @default.
• W1994249743 creator A5083511911 @default.
• W1994249743 creator A5088691462 @default.
• W1994249743 date "2009-08-01" @default.
• W1994249743 modified "2023-09-27" @default.
• W1994249743 title "Reversibility of Renal Impairment in Patients With Multiple Myeloma Treated With Bortezomib-Based Regimens: Identification of Predictive Factors" @default.
• W1994249743 cites W1520149138 @default.
• W1994249743 cites W1989803279 @default.
• W1994249743 cites W2001133874 @default.
• W1994249743 cites W2003056396 @default.
• W1994249743 cites W2025253157 @default.
• W1994249743 cites W2027071518 @default.
• W1994249743 cites W2055340704 @default.
• W1994249743 cites W2055864845 @default.
• W1994249743 cites W2081128344 @default.
• W1994249743 cites W2095328443 @default.
• W1994249743 cites W2096207943 @default.
• W1994249743 cites W2107154392 @default.
• W1994249743 cites W2108235071 @default.
• W1994249743 cites W2111039305 @default.
• W1994249743 cites W2120474651 @default.
• W1994249743 cites W2127760782 @default.
• W1994249743 cites W2550278449 @default.
• W1994249743 cites W2563593838 @default.
• W1994249743 cites W4241838501 @default.
• W1994249743 doi "https://doi.org/10.3816/clm.2009.n.059" @default.
• W1994249743 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19717380" @default.
• W1994249743 hasPublicationYear "2009" @default.
• W1994249743 type Work @default.
• W1994249743 sameAs 1994249743 @default.
• W1994249743 citedByCount "99" @default.
• W1994249743 countsByYear W19942497432012 @default.
• W1994249743 countsByYear W19942497432013 @default.
• W1994249743 countsByYear W19942497432014 @default.
• W1994249743 countsByYear W19942497432015 @default.
• W1994249743 countsByYear W19942497432016 @default.
• W1994249743 countsByYear W19942497432017 @default.
• W1994249743 countsByYear W19942497432018 @default.
• W1994249743 countsByYear W19942497432019 @default.
• W1994249743 countsByYear W19942497432020 @default.
• W1994249743 countsByYear W19942497432021 @default.
• W1994249743 countsByYear W19942497432022 @default.
• W1994249743 countsByYear W19942497432023 @default.
• W1994249743 crossrefType "journal-article" @default.
• W1994249743 hasAuthorship W1994249743A5004781025 @default.
• W1994249743 hasAuthorship W1994249743A5007766504 @default.
• W1994249743 hasAuthorship W1994249743A5018522443 @default.
• W1994249743 hasAuthorship W1994249743A5024471527 @default.
• W1994249743 hasAuthorship W1994249743A5040774907 @default.
• W1994249743 hasAuthorship W1994249743A5041407463 @default.
• W1994249743 hasAuthorship W1994249743A5046758725 @default.
• W1994249743 hasAuthorship W1994249743A5050531750 @default.
• W1994249743 hasAuthorship W1994249743A5051403132 @default.
• W1994249743 hasAuthorship W1994249743A5057736578 @default.
• W1994249743 hasAuthorship W1994249743A5083511911 @default.
• W1994249743 hasAuthorship W1994249743A5088691462 @default.
• W1994249743 hasConcept C126322002 @default.
• W1994249743 hasConcept C126894567 @default.
• W1994249743 hasConcept C159641895 @default.
• W1994249743 hasConcept C2776364478 @default.
• W1994249743 hasConcept C2777478702 @default.
• W1994249743 hasConcept C2779548226 @default.
• W1994249743 hasConcept C2779978075 @default.
• W1994249743 hasConcept C2780401358 @default.
• W1994249743 hasConcept C2780412452 @default.
• W1994249743 hasConcept C71924100 @default.
• W1994249743 hasConcept C90924648 @default.
• W1994249743 hasConceptScore W1994249743C126322002 @default.
• W1994249743 hasConceptScore W1994249743C126894567 @default.
• W1994249743 hasConceptScore W1994249743C159641895 @default.
• W1994249743 hasConceptScore W1994249743C2776364478 @default.
• W1994249743 hasConceptScore W1994249743C2777478702 @default.
• W1994249743 hasConceptScore W1994249743C2779548226 @default.
• W1994249743 hasConceptScore W1994249743C2779978075 @default.
• W1994249743 hasConceptScore W1994249743C2780401358 @default.
• W1994249743 hasConceptScore W1994249743C2780412452 @default.
• W1994249743 hasConceptScore W1994249743C71924100 @default.
• W1994249743 hasConceptScore W1994249743C90924648 @default.
• W1994249743 hasIssue "4" @default.
• W1994249743 hasLocation W19942497431 @default.
• W1994249743 hasLocation W19942497432 @default.
• W1994249743 hasOpenAccess W1994249743 @default.
• W1994249743 hasPrimaryLocation W19942497431 @default.
• W1994249743 hasRelatedWork W1934515323 @default.
• W1994249743 hasRelatedWork W2043144926 @default.
• W1994249743 hasRelatedWork W2053422287 @default.
• W1994249743 hasRelatedWork W2067661072 @default.

• next