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• W1994259060 abstract "Immunohistologic studies of 8 patients with squamous cell carcinoma (SCC) were undertaken using a series of monoclonal antibodies. In all of the patients, over 70% of the dermal infiltrates reacted with OKT3 and OKIal (HLA-DR), with a slight predominance of the OKT8+ suppressor/cytotoxic T subset (the mean OKT4/OKT8 ratio was 0.85). Both OKT4+ and OKT8+ subsets could be seen in contact with individual cancer cells. The percentage of OKB7+ (B) cells was less than 29% of the dermal infiltrates. Some Leu-7+ cells (less than 9% of the infiltrates) were seen in close association with individual cancer cells and none of these cells was present apart from the cancer cells. Few OKT6+ cells were observed in the papillary dermis and these had no relation to cancer cells. In the epidermis, OKT6+ dendritic cells remained within normal proportions. Staining with OKM1 revealed sporadic reactive cells. These results strongly suggest that besides T and B lymphocytes, Leu-7+ (natural killer) cells participate in a significant defense mechanism against SCC proliferation." @default.
• W1994259060 created "2016-06-24" @default.
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• W1994259060 date "1986-10-01" @default.
• W1994259060 modified "2023-09-26" @default.
• W1994259060 title "Immunohistologic Studies of Squamous Cell Carcinoma: Possible Participation of Leu-7+ (Natural Killer) Cells and Antitumor Effector Cells" @default.
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• W1994259060 doi "https://doi.org/10.1111/1523-1747.ep12455598" @default.
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