Matches in SemOpenAlex for { <https://semopenalex.org/work/W1994272912> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W1994272912 endingPage "163" @default.
- W1994272912 startingPage "159" @default.
- W1994272912 abstract "The protective action of thymol (paramethyl-isopropyl-phenol) was investigated against carbon tetrachloride (CCl(4))-induced hepatotoxicity in male Swiss albino mice. The CCl(4)at a dose of 20 microl kg(-1)produced damage to liver cells and was followed by the significant increase (P<0.001) in serum alanine aminotransferase (ALT) activity and hepatic lipid peroxidation after 24 h. The hepatocellular necrosis was further confirmed by histopathological examination of liver section. Oral administration of thymol in a single dose (300 mg kg(-1)) resulted in significant (P<0.05) amelioration of CCl(4)-induced hepatotoxicity. Thymol also inhibited lipid peroxidation induced by CCl(4)in vivo. The protection offered by thymol was also evident from histopathology photomicrograph. In a separate in vitro assay, thymol inhibited the non-enzymatic lipid peroxidation of normal mice liver homogenate induced by Fe(3+)-ascorbate. The present study suggests that thymol protects the liver against CCl(4)-induced toxicity and the protection may be mediated through its ability to inhibit lipid peroxidation. However, other interactions between thymol and CCl(4)remains to be elucidated. 1999 Academic Press." @default.
- W1994272912 created "2016-06-24" @default.
- W1994272912 creator A5027178689 @default.
- W1994272912 creator A5034616132 @default.
- W1994272912 creator A5053344822 @default.
- W1994272912 creator A5057966287 @default.
- W1994272912 creator A5076091965 @default.
- W1994272912 creator A5087312812 @default.
- W1994272912 date "1999-08-01" @default.
- W1994272912 modified "2023-10-16" @default.
- W1994272912 title "THE PROTECTIVE ACTION OF THYMOL AGAINST CARBON TETRACHLORIDE HEPATOTOXICITY IN MICE" @default.
- W1994272912 cites W1499850422 @default.
- W1994272912 cites W1579931350 @default.
- W1994272912 cites W1965938315 @default.
- W1994272912 cites W1966282630 @default.
- W1994272912 cites W1992650038 @default.
- W1994272912 cites W2029074995 @default.
- W1994272912 cites W2040904544 @default.
- W1994272912 cites W2044131495 @default.
- W1994272912 cites W2053054955 @default.
- W1994272912 cites W2066512225 @default.
- W1994272912 cites W2083228186 @default.
- W1994272912 cites W2104828542 @default.
- W1994272912 cites W2105342603 @default.
- W1994272912 doi "https://doi.org/10.1006/phrs.1999.0472" @default.
- W1994272912 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10433875" @default.
- W1994272912 hasPublicationYear "1999" @default.
- W1994272912 type Work @default.
- W1994272912 sameAs 1994272912 @default.
- W1994272912 citedByCount "53" @default.
- W1994272912 countsByYear W19942729122012 @default.
- W1994272912 countsByYear W19942729122013 @default.
- W1994272912 countsByYear W19942729122014 @default.
- W1994272912 countsByYear W19942729122015 @default.
- W1994272912 countsByYear W19942729122016 @default.
- W1994272912 countsByYear W19942729122017 @default.
- W1994272912 countsByYear W19942729122018 @default.
- W1994272912 countsByYear W19942729122019 @default.
- W1994272912 countsByYear W19942729122020 @default.
- W1994272912 countsByYear W19942729122021 @default.
- W1994272912 countsByYear W19942729122022 @default.
- W1994272912 countsByYear W19942729122023 @default.
- W1994272912 crossrefType "journal-article" @default.
- W1994272912 hasAuthorship W1994272912A5027178689 @default.
- W1994272912 hasAuthorship W1994272912A5034616132 @default.
- W1994272912 hasAuthorship W1994272912A5053344822 @default.
- W1994272912 hasAuthorship W1994272912A5057966287 @default.
- W1994272912 hasAuthorship W1994272912A5076091965 @default.
- W1994272912 hasAuthorship W1994272912A5087312812 @default.
- W1994272912 hasConcept C178790620 @default.
- W1994272912 hasConcept C185592680 @default.
- W1994272912 hasConcept C2777278459 @default.
- W1994272912 hasConcept C2777359374 @default.
- W1994272912 hasConcept C2778004101 @default.
- W1994272912 hasConcept C2780642067 @default.
- W1994272912 hasConcept C2780829032 @default.
- W1994272912 hasConcept C29730261 @default.
- W1994272912 hasConcept C43617362 @default.
- W1994272912 hasConcept C55493867 @default.
- W1994272912 hasConcept C71924100 @default.
- W1994272912 hasConcept C98274493 @default.
- W1994272912 hasConceptScore W1994272912C178790620 @default.
- W1994272912 hasConceptScore W1994272912C185592680 @default.
- W1994272912 hasConceptScore W1994272912C2777278459 @default.
- W1994272912 hasConceptScore W1994272912C2777359374 @default.
- W1994272912 hasConceptScore W1994272912C2778004101 @default.
- W1994272912 hasConceptScore W1994272912C2780642067 @default.
- W1994272912 hasConceptScore W1994272912C2780829032 @default.
- W1994272912 hasConceptScore W1994272912C29730261 @default.
- W1994272912 hasConceptScore W1994272912C43617362 @default.
- W1994272912 hasConceptScore W1994272912C55493867 @default.
- W1994272912 hasConceptScore W1994272912C71924100 @default.
- W1994272912 hasConceptScore W1994272912C98274493 @default.
- W1994272912 hasIssue "2" @default.
- W1994272912 hasLocation W19942729121 @default.
- W1994272912 hasLocation W19942729122 @default.
- W1994272912 hasOpenAccess W1994272912 @default.
- W1994272912 hasPrimaryLocation W19942729121 @default.
- W1994272912 hasRelatedWork W1518790293 @default.
- W1994272912 hasRelatedWork W1977417934 @default.
- W1994272912 hasRelatedWork W1994272912 @default.
- W1994272912 hasRelatedWork W2012139103 @default.
- W1994272912 hasRelatedWork W2044528820 @default.
- W1994272912 hasRelatedWork W2067009374 @default.
- W1994272912 hasRelatedWork W2187200446 @default.
- W1994272912 hasRelatedWork W2410667830 @default.
- W1994272912 hasRelatedWork W3006814219 @default.
- W1994272912 hasRelatedWork W4225671786 @default.
- W1994272912 hasVolume "40" @default.
- W1994272912 isParatext "false" @default.
- W1994272912 isRetracted "false" @default.
- W1994272912 magId "1994272912" @default.
- W1994272912 workType "article" @default.