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- W1994282169 endingPage "457" @default.
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- W1994282169 abstract "Formation and adaptation of metabolic networks has been a long-standing question in biology. With recent developments in biotechnology and bioinformatics, the understanding of metabolism is progressively becoming clearer from a network perspective. This review introduces the comprehensive metabolic world that has been revealed by a wide range of data analyses and theoretical studies; in particular, it illustrates the role of evolutionary events, such as gene duplication and horizontal gene transfer, and environmental factors, such as nutrient availability and growth conditions, in evolution of the metabolic network. Furthermore, the mathematical models for the formation and adaptation of metabolic networks have also been described, according to the current understanding from a perspective of metabolic networks. These recent findings are helpful in not only understanding the formation of metabolic networks and their adaptation, but also metabolic engineering." @default.
- W1994282169 created "2016-06-24" @default.
- W1994282169 creator A5013426338 @default.
- W1994282169 date "2012-07-12" @default.
- W1994282169 modified "2023-09-27" @default.
- W1994282169 title "Current Understanding of the Formation and Adaptation of Metabolic Systems Based on Network Theory" @default.
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