Matches in SemOpenAlex for { <https://semopenalex.org/work/W1994363463> ?p ?o ?g. }
- W1994363463 endingPage "30" @default.
- W1994363463 startingPage "30" @default.
- W1994363463 abstract "The formation of the mammalian central nervous system requires the establishment of complex neural circuits between a diverse array of neuronal subtypes. Here we report that the proneural transcription factor Neurogenin2 (Ngn2) is crucial for the proper specification of cortical axon projections.The genetic loss of Ngn2 in mice results in fewer callosal axons projecting towards the midline as well as abnormal midline crossing. shRNA-mediated knockdown of Ngn2 revealed its cell-autonomous requirement for the proper projection of axons from layer 2/3 pyramidal neurons to the midline in vivo. We found that the acute loss of Ngn2 in vivo induces the axon of superficial layer 2/3 neurons to project laterally towards aberrant cortical and subcortical targets.These and previous results demonstrate that Ngn2 is required for the coordinated specification of cardinal features defining the phenotype of cortical pyramidal neurons, including their migration properties, dendritic morphology and axonal projection." @default.
- W1994363463 created "2016-06-24" @default.
- W1994363463 creator A5002062661 @default.
- W1994363463 creator A5041300271 @default.
- W1994363463 date "2011-01-01" @default.
- W1994363463 modified "2023-09-30" @default.
- W1994363463 title "Neurogenin2 regulates the initial axon guidance of cortical pyramidal neurons projecting medially to the corpus callosum" @default.
- W1994363463 cites W1503727145 @default.
- W1994363463 cites W1970302470 @default.
- W1994363463 cites W1990500865 @default.
- W1994363463 cites W1990935914 @default.
- W1994363463 cites W1991732233 @default.
- W1994363463 cites W1995784214 @default.
- W1994363463 cites W1996090115 @default.
- W1994363463 cites W2003541496 @default.
- W1994363463 cites W2015218300 @default.
- W1994363463 cites W2021253017 @default.
- W1994363463 cites W2027176344 @default.
- W1994363463 cites W2035022202 @default.
- W1994363463 cites W2047452007 @default.
- W1994363463 cites W2051409024 @default.
- W1994363463 cites W2055190734 @default.
- W1994363463 cites W2060902761 @default.
- W1994363463 cites W2064520670 @default.
- W1994363463 cites W2072966096 @default.
- W1994363463 cites W2078284356 @default.
- W1994363463 cites W2081092833 @default.
- W1994363463 cites W2095711264 @default.
- W1994363463 cites W2098867949 @default.
- W1994363463 cites W2099642308 @default.
- W1994363463 cites W2106605041 @default.
- W1994363463 cites W2107784170 @default.
- W1994363463 cites W2124142272 @default.
- W1994363463 cites W2127220436 @default.
- W1994363463 cites W2132847407 @default.
- W1994363463 cites W2134711325 @default.
- W1994363463 cites W2148212562 @default.
- W1994363463 doi "https://doi.org/10.1186/1749-8104-6-30" @default.
- W1994363463 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3174110" @default.
- W1994363463 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21864333" @default.
- W1994363463 hasPublicationYear "2011" @default.
- W1994363463 type Work @default.
- W1994363463 sameAs 1994363463 @default.
- W1994363463 citedByCount "85" @default.
- W1994363463 countsByYear W19943634632012 @default.
- W1994363463 countsByYear W19943634632013 @default.
- W1994363463 countsByYear W19943634632014 @default.
- W1994363463 countsByYear W19943634632015 @default.
- W1994363463 countsByYear W19943634632016 @default.
- W1994363463 countsByYear W19943634632017 @default.
- W1994363463 countsByYear W19943634632018 @default.
- W1994363463 countsByYear W19943634632019 @default.
- W1994363463 countsByYear W19943634632020 @default.
- W1994363463 countsByYear W19943634632021 @default.
- W1994363463 countsByYear W19943634632022 @default.
- W1994363463 countsByYear W19943634632023 @default.
- W1994363463 crossrefType "journal-article" @default.
- W1994363463 hasAuthorship W1994363463A5002062661 @default.
- W1994363463 hasAuthorship W1994363463A5041300271 @default.
- W1994363463 hasBestOaLocation W19943634631 @default.
- W1994363463 hasConcept C104317684 @default.
- W1994363463 hasConcept C105702510 @default.
- W1994363463 hasConcept C127955056 @default.
- W1994363463 hasConcept C148762608 @default.
- W1994363463 hasConcept C169760540 @default.
- W1994363463 hasConcept C173396325 @default.
- W1994363463 hasConcept C2778183499 @default.
- W1994363463 hasConcept C2778437258 @default.
- W1994363463 hasConcept C2779530196 @default.
- W1994363463 hasConcept C529278444 @default.
- W1994363463 hasConcept C54355233 @default.
- W1994363463 hasConcept C69125201 @default.
- W1994363463 hasConcept C86803240 @default.
- W1994363463 hasConceptScore W1994363463C104317684 @default.
- W1994363463 hasConceptScore W1994363463C105702510 @default.
- W1994363463 hasConceptScore W1994363463C127955056 @default.
- W1994363463 hasConceptScore W1994363463C148762608 @default.
- W1994363463 hasConceptScore W1994363463C169760540 @default.
- W1994363463 hasConceptScore W1994363463C173396325 @default.
- W1994363463 hasConceptScore W1994363463C2778183499 @default.
- W1994363463 hasConceptScore W1994363463C2778437258 @default.
- W1994363463 hasConceptScore W1994363463C2779530196 @default.
- W1994363463 hasConceptScore W1994363463C529278444 @default.
- W1994363463 hasConceptScore W1994363463C54355233 @default.
- W1994363463 hasConceptScore W1994363463C69125201 @default.
- W1994363463 hasConceptScore W1994363463C86803240 @default.
- W1994363463 hasIssue "1" @default.
- W1994363463 hasLocation W19943634631 @default.
- W1994363463 hasLocation W19943634632 @default.
- W1994363463 hasLocation W19943634633 @default.
- W1994363463 hasLocation W19943634634 @default.
- W1994363463 hasLocation W19943634635 @default.
- W1994363463 hasOpenAccess W1994363463 @default.
- W1994363463 hasPrimaryLocation W19943634631 @default.
- W1994363463 hasRelatedWork W1961849937 @default.
- W1994363463 hasRelatedWork W1965347681 @default.
- W1994363463 hasRelatedWork W1994363463 @default.
- W1994363463 hasRelatedWork W2030150951 @default.