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- W1994367088 abstract "Abstract— α‐Bungarotoxin (α‐BuTX) has been used as a marker for studying the acetylcholine receptors (AChRs) in the superior cervical ganglion (SCG) of the adult rat. Binding of [ 125 I]α‐BuTX to detergent‐solubilized AChRs from rat SCG is a saturable and practically irreversible process. The rate constant of association of the toxin‐receptor complex is 1.66 × 10 5 M −1 S −1 . The receptor is of nicotinic type. One SCG of adult rat binds about 57 fmol of [ 125 I]α‐BuTX corresponding to 9.2 × 10 5 AChRs per sympathetic neuron. Light microscope autoradiography shows that AChRs are mainly localized along neuronal processes (probably dendrites). The perikarya exhibit a weak radioactive reaction, while the nerve fibres are devoid of AChRs. Following preganglionic denervation the number of AChRs never increases and their spatial distribution seems not to change." @default.
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- W1994367088 date "1976-07-01" @default.
- W1994367088 modified "2023-10-09" @default.
- W1994367088 title "ACETYLCHOLINE RECEPTORS: NUMBER and DISTRIBUTION IN INTACT and DEAFFERENTED SUPERIOR CERVICAL GANGLION OF THE RAT" @default.
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- W1994367088 doi "https://doi.org/10.1111/j.1471-4159.1976.tb01542.x" @default.
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