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- W1994373921 abstract "To compare the results of a minimal-stimulation protocol with those of a standard protocol used for IVF.Retrospective, controlled study.University center.Fifty-five patients undergoing IVF using a minimal-stimulation protocol with or without adjuvant therapy with a GnRH antagonist. A control group consisted of age- and diagnosis-matched patients undergoing a standard long GnRH agonist (GnRH-a)-gonadotropin stimulation during the same time period.Clomiphene citrate and gonadotropins, with or without the GnRH antagonist ganirelix.Oocytes recovered and pregnancy rates.The number of oocytes retrieved was significantly lower for the minimal-stimulation regimen compared with the case of the long GnRH-a protocol (4.8 +/- 2.6 vs. 16.2 +/- 7.5, respectively). The clinical pregnancy rate per transfer, however, was not significantly different between the two regimens (37% vs. 41%, minimal stimulation vs. long GnRH-a protocol, respectively). The addition of ganirelix resulted in at least the same pregnancy outcome as compared with the case of cycles without the antagonist.Minimal stimulation using clomiphene citrate followed by gonadotropin for IVF results in pregnancy rates equal to the standard long GnRH-a-gonadotropin protocol. The addition of ganirelix resulted in at least similar results with the advantage of eliminating the occurrence of a premature endogenous LH surge." @default.
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- W1994373921 date "2002-11-01" @default.
- W1994373921 modified "2023-09-25" @default.
- W1994373921 title "Minimal ovarian hyperstimulation for in vitro fertilization using sequential clomiphene citrate and gonadotropin with or without the addition of a gonadotropin-releasing hormone antagonist" @default.
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- W1994373921 doi "https://doi.org/10.1016/s0015-0282(02)03374-5" @default.
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