Matches in SemOpenAlex for { <https://semopenalex.org/work/W1994378892> ?p ?o ?g. }
- W1994378892 endingPage "32" @default.
- W1994378892 startingPage "25" @default.
- W1994378892 abstract "Several lines of evidence support the association between low or lowered levels of serum total cholesterol and suicide. Genetic epidemiological studies suggest that genes predispose to suicide. Given that genes control many aspects of cholesterol biosynthesis and metabolism, one approach through which to explore the putative association between low cholesterol and suicide is through genetic studies.We examined the potential role of five genes encoding proteins involved in cholesterol biosynthesis and transport in a total sample of 305 male Caucasian subjects, consisting of 145 suicide completers and 160 controls. We investigated variation in the HMG CoA reductase (HMGCR), 7-dehydrocholesterol reductase (DHCR7), lipoprotein lipase (LPL), low-density lipoprotein receptor (LDLR), and apolipoprotein E (APOE) genes.We were unable to detect significant differences in allele or genotype frequencies between the suicide cases and controls for any of the genes studied. No relationship was found between genotype and impulsivity or aggression as measured using the BIS and BDHI, respectively.The limitations of this study are consistent with the typical limitations inherent in most genetic association studies involving complex behavioral traits.Although these genes are unlikely to play a major role in susceptibility to suicide, further studies in a larger sample are necessary to reveal the smaller genetic effects, if present." @default.
- W1994378892 created "2016-06-24" @default.
- W1994378892 creator A5002118289 @default.
- W1994378892 creator A5007266609 @default.
- W1994378892 creator A5024325808 @default.
- W1994378892 creator A5054473156 @default.
- W1994378892 creator A5058497367 @default.
- W1994378892 creator A5080411041 @default.
- W1994378892 creator A5085745714 @default.
- W1994378892 date "2004-04-01" @default.
- W1994378892 modified "2023-10-16" @default.
- W1994378892 title "Investigation of completed suicide and genes involved in cholesterol metabolism" @default.
- W1994378892 cites W1683373906 @default.
- W1994378892 cites W1770880387 @default.
- W1994378892 cites W1974384388 @default.
- W1994378892 cites W1984058728 @default.
- W1994378892 cites W1997874485 @default.
- W1994378892 cites W1997959046 @default.
- W1994378892 cites W2006610663 @default.
- W1994378892 cites W2017066949 @default.
- W1994378892 cites W2022149167 @default.
- W1994378892 cites W2027211599 @default.
- W1994378892 cites W2029150533 @default.
- W1994378892 cites W2041343757 @default.
- W1994378892 cites W2042103448 @default.
- W1994378892 cites W2050971515 @default.
- W1994378892 cites W2067429432 @default.
- W1994378892 cites W2075506309 @default.
- W1994378892 cites W2082008328 @default.
- W1994378892 cites W2082108363 @default.
- W1994378892 cites W2121833889 @default.
- W1994378892 cites W2134725514 @default.
- W1994378892 cites W2161869952 @default.
- W1994378892 cites W2169484904 @default.
- W1994378892 cites W2223398576 @default.
- W1994378892 doi "https://doi.org/10.1016/s0165-0327(02)00453-6" @default.
- W1994378892 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15023477" @default.
- W1994378892 hasPublicationYear "2004" @default.
- W1994378892 type Work @default.
- W1994378892 sameAs 1994378892 @default.
- W1994378892 citedByCount "21" @default.
- W1994378892 countsByYear W19943788922012 @default.
- W1994378892 countsByYear W19943788922014 @default.
- W1994378892 countsByYear W19943788922016 @default.
- W1994378892 countsByYear W19943788922017 @default.
- W1994378892 countsByYear W19943788922020 @default.
- W1994378892 countsByYear W19943788922021 @default.
- W1994378892 countsByYear W19943788922022 @default.
- W1994378892 crossrefType "journal-article" @default.
- W1994378892 hasAuthorship W1994378892A5002118289 @default.
- W1994378892 hasAuthorship W1994378892A5007266609 @default.
- W1994378892 hasAuthorship W1994378892A5024325808 @default.
- W1994378892 hasAuthorship W1994378892A5054473156 @default.
- W1994378892 hasAuthorship W1994378892A5058497367 @default.
- W1994378892 hasAuthorship W1994378892A5080411041 @default.
- W1994378892 hasAuthorship W1994378892A5085745714 @default.
- W1994378892 hasConcept C104317684 @default.
- W1994378892 hasConcept C118552586 @default.
- W1994378892 hasConcept C126322002 @default.
- W1994378892 hasConcept C134018914 @default.
- W1994378892 hasConcept C134651460 @default.
- W1994378892 hasConcept C135763542 @default.
- W1994378892 hasConcept C180754005 @default.
- W1994378892 hasConcept C181199279 @default.
- W1994378892 hasConcept C2778163477 @default.
- W1994378892 hasConcept C2779134260 @default.
- W1994378892 hasConcept C2780319597 @default.
- W1994378892 hasConcept C2780842732 @default.
- W1994378892 hasConcept C3017944768 @default.
- W1994378892 hasConcept C526869908 @default.
- W1994378892 hasConcept C54355233 @default.
- W1994378892 hasConcept C545542383 @default.
- W1994378892 hasConcept C55493867 @default.
- W1994378892 hasConcept C57089818 @default.
- W1994378892 hasConcept C62746215 @default.
- W1994378892 hasConcept C71924100 @default.
- W1994378892 hasConcept C86803240 @default.
- W1994378892 hasConceptScore W1994378892C104317684 @default.
- W1994378892 hasConceptScore W1994378892C118552586 @default.
- W1994378892 hasConceptScore W1994378892C126322002 @default.
- W1994378892 hasConceptScore W1994378892C134018914 @default.
- W1994378892 hasConceptScore W1994378892C134651460 @default.
- W1994378892 hasConceptScore W1994378892C135763542 @default.
- W1994378892 hasConceptScore W1994378892C180754005 @default.
- W1994378892 hasConceptScore W1994378892C181199279 @default.
- W1994378892 hasConceptScore W1994378892C2778163477 @default.
- W1994378892 hasConceptScore W1994378892C2779134260 @default.
- W1994378892 hasConceptScore W1994378892C2780319597 @default.
- W1994378892 hasConceptScore W1994378892C2780842732 @default.
- W1994378892 hasConceptScore W1994378892C3017944768 @default.
- W1994378892 hasConceptScore W1994378892C526869908 @default.
- W1994378892 hasConceptScore W1994378892C54355233 @default.
- W1994378892 hasConceptScore W1994378892C545542383 @default.
- W1994378892 hasConceptScore W1994378892C55493867 @default.
- W1994378892 hasConceptScore W1994378892C57089818 @default.
- W1994378892 hasConceptScore W1994378892C62746215 @default.
- W1994378892 hasConceptScore W1994378892C71924100 @default.
- W1994378892 hasConceptScore W1994378892C86803240 @default.