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- W1994400552 abstract "In this era of personalized cancer therapies, there has never been a more important value on the availability of high-quality tissue collection for our cancer patients. Current evidence with new biomarkers and gene arrays make it patently clear that our vocabulary of using a single cancer label (eg, breast cancer) based on the light microscopic diagnosis is actually outmoded! We now know that within that light microscopic diagnosis is a very heterogeneous group of cancers when examined with genetic and molecular approaches. Furthermore, to provide the appropriate cancer treatment, we must calibrate our multidisciplinary treatment plan according to the risk of local recurrences and metastatic disease as reflected in the characteristics of the patients’ own can cer . . . which can vary from very low to very high. The single label based on light microscopic diagnosis and TNM staging criteria provide an initial formulation of metastatic risk, but we can increasingly get into an even more reliable prediction of metastatic risk for an individual patient based on biomarkers, at least for some cancers, such as breast, colorectal, and lung cancers as well as leukemias and lymphomas." @default.
- W1994400552 created "2016-06-24" @default.
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- W1994400552 date "2011-06-01" @default.
- W1994400552 modified "2023-09-23" @default.
- W1994400552 title "Reexamining Our Routines of Handing Surgical Tissue in the Operating Room" @default.
- W1994400552 doi "https://doi.org/10.1093/jncimonographs/lgr001" @default.
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