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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1994421111> ?p ?o ?g. }

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• W1994421111 abstract "Chemical modification studies provide evidence that single-stranded oligodeoxyribonucleotides can form stable intrastrand triple helices. Two oligonucleotides of opposite polarity were synthesized, each composed of a homopurine-homopyrimidine hairpin stem linked to a pyrimidine sequence which is capable of folding back on the hairpin stem and forming specific Hoogsteen hydrogen bonds. Using potassium permanganate as a chemical modification reagent, we have found that two oligodeoxyribonucleotides of sequence composition type 5'-(purine)8(N)4(pyrimidine)8(N)6(pyrimidine)8-3' and 5'-(pyrimidine)8N6(pyrimidine)8N4(purine)8-3' undergo dramatic structural changes consistent with intrastrand DNA triple-helix formation induced by lowering the pH or raising the Mg2+ concentration. The intrastrand DNA triple helix is sensitive to base mismatches." @default.
• W1994421111 created "2016-06-24" @default.
• W1994421111 creator A5062574140 @default.
• W1994421111 creator A5076578241 @default.
• W1994421111 date "1990-10-01" @default.
• W1994421111 modified "2023-10-16" @default.
• W1994421111 title "Single-strand DNA triple-helix formation" @default.
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• W1994421111 doi "https://doi.org/10.1021/bi00494a001" @default.
• W1994421111 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2271614" @default.
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