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• W1994426246 startingPage "1854" @default.
• W1994426246 abstract "The heteroleptic complexes, [(MePhtpy)RuCl(dpp)](PF6) and [(tpy)RuCl(dpp)](PF6), have been synthesized, characterized, and investigated with respect to their photophysical, redox, and DNA photocleavage properties (where MePhtpy = 4′-(4-methylphenyl)-2,2′:6′,2′′-terpyridine and dpp = 2,3-bis(2-pyridyl)pyrazine, tpy = 2,2′:6′,2′′-terpyridine). The X-ray crystal structure confirms the identity of the new [(MePhtpy)RuCl(dpp)](PF6) complex. These heteroleptic complexes were found to photocleave DNA in the presence of oxygen, unlike the previously studied complex, [Ru(tpy)2](PF6)2. The photophysical, redox, and DNA photocleavage properties of the heteroleptic complexes were compared with those of the homoleptic complexes, [Ru(MePhtpy)2](PF6)2 and [Ru(tpy)2](PF6)2. The heteroleptic complexes showed intense metal to ligand charge transfer (MLCT) transition at lower energy ([(MePhtpy)RuCl(dpp)](PF6), 522 nm; [(tpy)RuCl(dpp)](PF6), 516 nm) and longer excited state lifetimes as compared to the homoleptic complexes. The [Ru(MePhtpy)2]2+ complex was found to photocleave DNA in contrast to [Ru(tpy)2]2+. The introduction of a methylphenyl group on the tepyridine ligand not only enhances the 3MLCT excited state lifetime but also increases the lipophilicity and thereby the DNA binding ability of the molecule. An increase in lipophilicity upon addition of a methylphenyl group on the 2,2′:6′,2′′-terpyridine ligand was confirmed by determination of the partition coefficient ([(MePhtpy)RuCl(dpp)](PF6), log P = +1.16; [(tpy)RuCl(dpp)](PF6), log P = −1.27). The heteroleptic complexes photocleave DNA more efficiently than the homoleptic complexes, with the greatest activity being observed for the newly prepared [(MePhtpy)RuCl(dpp)](PF6) complex." @default.
• W1994426246 created "2016-06-24" @default.
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• W1994426246 date "2008-10-01" @default.
• W1994426246 modified "2023-09-24" @default.
• W1994426246 title "Enhanced DNA photocleavage properties of Ru(II) terpyridine complexes upon incorporation of methylphenyl substituted terpyridine and/or the polyazine bridging ligand dpp (2,3-bis(2-pyridyl)pyrazine)" @default.
• W1994426246 cites W1963980943 @default.
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• W1994426246 cites W1969206362 @default.
• W1994426246 cites W1970393749 @default.
• W1994426246 cites W1975159473 @default.
• W1994426246 cites W1984668192 @default.
• W1994426246 cites W1988558974 @default.
• W1994426246 cites W1989651677 @default.
• W1994426246 cites W1990218577 @default.
• W1994426246 cites W1999153581 @default.
• W1994426246 cites W1999620489 @default.
• W1994426246 cites W2000231152 @default.
• W1994426246 cites W2003964827 @default.
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• W1994426246 cites W2016738144 @default.
• W1994426246 cites W2019194950 @default.
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• W1994426246 cites W2022967113 @default.
• W1994426246 cites W2029136727 @default.
• W1994426246 cites W2035752597 @default.
• W1994426246 cites W2037747241 @default.
• W1994426246 cites W2041459118 @default.
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• W1994426246 cites W2051345608 @default.
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• W1994426246 cites W2062018658 @default.
• W1994426246 cites W2066917416 @default.
• W1994426246 cites W2080582278 @default.
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• W1994426246 cites W2086044791 @default.
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• W1994426246 cites W223634589 @default.
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• W1994426246 cites W2949485030 @default.
• W1994426246 cites W2951794441 @default.
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• W1994426246 doi "https://doi.org/10.1016/j.jinorgbio.2008.06.004" @default.
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