Matches in SemOpenAlex for { <https://semopenalex.org/work/W1994430021> ?p ?o ?g. }
- W1994430021 abstract "Exposure to stressful stimuli causes activation of the hypothalamic-pituitary-adrenal axis which rapidly releases high concentrations of glucocorticoid stress hormones, resulting in increased cellular metabolism and spontaneous oxygen and nitrogen radical formation. High concentrations of nitrogen radicals, including nitric oxide, cause damage to cellular proteins in addition to inhibiting components of the mitochondrial transport chain, leading to cellular energy deficiency. During stress exposure, pharmacological inhibition of nitric oxide production reduces indicators of anxiety- and depressive-like behavior in animal models. Therefore, the purpose of this review is to present an overview of the current literature on stress-evoked changes in the nitrergic system, particularly within neural tissue." @default.
- W1994430021 created "2016-06-24" @default.
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- W1994430021 date "2015-01-21" @default.
- W1994430021 modified "2023-09-30" @default.
- W1994430021 title "Response of the nitrergic system to activation of the neuroendocrine stress axis" @default.
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- W1994430021 doi "https://doi.org/10.3389/fnins.2015.00003" @default.
- W1994430021 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4300918" @default.
- W1994430021 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25653586" @default.
- W1994430021 hasPublicationYear "2015" @default.
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