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- W1994436090 abstract "Twins concordant for elevated alpha-fetoprotein (AFP) and acetylcholinesterase (AChE) and discordant for neural tube defect (NTD) and sex are reported. A literature review reveals instances of termination of twin pregnancies with one normal and one abnormal fetus, partly based on concordant high AFP and positive AChE (although discordant on ultrasound examination). The levels of AFP and AChE in twin pregnancies are probably a function of the number of layers of fetal membranes separating twin sacs; dichorionic, diamniotic membranes allow transfer of AFP; monochorionic, diamniotic membranes allow transfer of both AFP and AChE. Cautious interpretation of biochemical findings and reliance on high resolution ultrasonography are suggested." @default.
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- W1994436090 date "1989-12-01" @default.
- W1994436090 modified "2023-09-27" @default.
- W1994436090 title "Alpha-fetoprotein and acetylcholinesterase in twins discordant for neural tube defect" @default.
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- W1994436090 doi "https://doi.org/10.1002/pd.1970091203" @default.
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