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- W1994440138 abstract "The interaction between dipyridamole and nitric oxide (NO) was studied using isolated rabbit platelets and segments of the rabbit aorta. Dipyridamole potentiated the anti-aggregating activity of authentic NO when platelet aggregation was induced by the thromboxane A2 mimetic U-46619 or adenosine diphosphate (ADP). This potentiation was also seen when washed rabbit platelets were exposed to aortic effluent containing endothelium-derived NO. In the thoracic aorta dipyridamole hardly influenced the endothelium-dependent relaxations induced by acetylcholine. However, dipyridamole clearly enhanced the dilatation caused by exogenous NO from four different sources, including endothelial cells." @default.
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- W1994440138 date "1991-06-01" @default.
- W1994440138 modified "2023-09-27" @default.
- W1994440138 title "Dipyridamole potentiates the anti-aggregating and vasodilator activity of nitric oxide" @default.
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- W1994440138 doi "https://doi.org/10.1016/0014-2999(91)90629-5" @default.
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