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- W1994447768 endingPage "803" @default.
- W1994447768 startingPage "794" @default.
- W1994447768 abstract "The hypothalamic–pituitary–adrenal axis has been the focus of extensive research with regard to the phenotypic plasticity this system shows in response to environmental influences on mammalian development. This review proposes that the mesolimbic dopamine system is similarly reactive to indicators of environmental adversity during development. Physical, physiological, and toxicological stressors encountered during perinatal development have been routinely demonstrated to affect dopamine neurophysiology, most likely through consequent exposure to maternal glucocorticoids or a reduction in oxygen supply. However, findings remain inconsistent with regard to the nature of impact these events have on the dopamine system. Both hyper- and hypo-dopaminergic changes have been noted. This review argues that the directionality of change is a function of chronicity and severity of the insult, and that both resultant phenotypes are adaptive developmental responses, despite their potential for conferring vulnerability for psychopathology in humans." @default.
- W1994447768 created "2016-06-24" @default.
- W1994447768 creator A5006234057 @default.
- W1994447768 date "2011-01-01" @default.
- W1994447768 modified "2023-09-25" @default.
- W1994447768 title "The canary in the coalmine: The sensitivity of mesolimbic dopamine to environmental adversity during development" @default.
- W1994447768 cites W1511351296 @default.
- W1994447768 cites W1863530899 @default.
- W1994447768 cites W1963623154 @default.
- W1994447768 cites W1964709010 @default.
- W1994447768 cites W1966733439 @default.
- W1994447768 cites W1967097120 @default.
- W1994447768 cites W1968360820 @default.
- W1994447768 cites W1968490092 @default.
- W1994447768 cites W1972793459 @default.
- W1994447768 cites W1975310219 @default.
- W1994447768 cites W1975422535 @default.
- W1994447768 cites W1975801973 @default.
- W1994447768 cites W1975905871 @default.
- W1994447768 cites W1976177962 @default.
- W1994447768 cites W1980698842 @default.
- W1994447768 cites W1980873368 @default.
- W1994447768 cites W1981353792 @default.
- W1994447768 cites W1984224154 @default.
- W1994447768 cites W1984357169 @default.
- W1994447768 cites W1985771124 @default.
- W1994447768 cites W1987052302 @default.
- W1994447768 cites W1988645552 @default.
- W1994447768 cites W1990352228 @default.
- W1994447768 cites W1991662616 @default.
- W1994447768 cites W1994740828 @default.
- W1994447768 cites W1997901565 @default.
- W1994447768 cites W2004000125 @default.
- W1994447768 cites W2004709703 @default.
- W1994447768 cites W2005855977 @default.
- W1994447768 cites W2005986508 @default.
- W1994447768 cites W2007005063 @default.
- W1994447768 cites W2011412551 @default.
- W1994447768 cites W2012541271 @default.
- W1994447768 cites W2013222700 @default.
- W1994447768 cites W2013991501 @default.
- W1994447768 cites W2014463076 @default.
- W1994447768 cites W2015933168 @default.
- W1994447768 cites W2017342359 @default.
- W1994447768 cites W2018328822 @default.
- W1994447768 cites W2018825306 @default.
- W1994447768 cites W2020087983 @default.
- W1994447768 cites W2020874462 @default.
- W1994447768 cites W2021641010 @default.
- W1994447768 cites W2021741218 @default.
- W1994447768 cites W2024647991 @default.
- W1994447768 cites W2026754914 @default.
- W1994447768 cites W2029004410 @default.
- W1994447768 cites W2029383690 @default.
- W1994447768 cites W2031092093 @default.
- W1994447768 cites W2034323432 @default.
- W1994447768 cites W2034607657 @default.
- W1994447768 cites W2034671680 @default.
- W1994447768 cites W2035421326 @default.
- W1994447768 cites W2036621839 @default.
- W1994447768 cites W2038647795 @default.
- W1994447768 cites W2043435297 @default.
- W1994447768 cites W2045512428 @default.
- W1994447768 cites W2047907599 @default.
- W1994447768 cites W2051083217 @default.
- W1994447768 cites W2054692302 @default.
- W1994447768 cites W2054695597 @default.
- W1994447768 cites W2055018246 @default.
- W1994447768 cites W2055686502 @default.
- W1994447768 cites W2056511780 @default.
- W1994447768 cites W2064837367 @default.
- W1994447768 cites W2064885604 @default.
- W1994447768 cites W2066689003 @default.
- W1994447768 cites W2066704280 @default.
- W1994447768 cites W2067276124 @default.
- W1994447768 cites W2069396003 @default.
- W1994447768 cites W2070333110 @default.
- W1994447768 cites W2073992819 @default.
- W1994447768 cites W2077499677 @default.
- W1994447768 cites W2077923551 @default.
- W1994447768 cites W2079353098 @default.
- W1994447768 cites W2080783135 @default.
- W1994447768 cites W2084114882 @default.
- W1994447768 cites W2088475596 @default.
- W1994447768 cites W2091793105 @default.
- W1994447768 cites W2092264405 @default.
- W1994447768 cites W2093005961 @default.
- W1994447768 cites W2096338275 @default.
- W1994447768 cites W2096596646 @default.
- W1994447768 cites W2098534820 @default.
- W1994447768 cites W2099128126 @default.
- W1994447768 cites W2103550033 @default.
- W1994447768 cites W2103839002 @default.
- W1994447768 cites W2103902275 @default.
- W1994447768 cites W2106839751 @default.
- W1994447768 cites W2109059823 @default.
- W1994447768 cites W2116658855 @default.
- W1994447768 cites W2120743339 @default.