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- W1994450164 abstract "The signal transducer and activator of transcription-2 (STAT2) was discovered as a cellular component of the DNA binding complex known as interferon (IFN) stimulated gene factor-3. Numerous studies have confirmed that STAT2 operates as a positive regulator in the transcriptional activation response elicited by IFNs. In this article, we highlight the progress made in elucidating the pivotal role of STAT2 in driving the expression of IFN-induced genes, innate antiviral immunity, apoptosis, and cancer. A better understanding of the functional role of STAT2 in the IFN response and how STAT2 is regulated will uncover new clues to its role in diseases." @default.
- W1994450164 created "2016-06-24" @default.
- W1994450164 creator A5057364209 @default.
- W1994450164 creator A5065749484 @default.
- W1994450164 date "2012-03-01" @default.
- W1994450164 modified "2023-10-18" @default.
- W1994450164 title "The Role of Signal Transducer and Activator of Transcription-2 in the Interferon Response" @default.
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- W1994450164 doi "https://doi.org/10.1089/jir.2011.0099" @default.
- W1994450164 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3680977" @default.
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