FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1994459789> ?p ?o ?g. }

• W1994459789 abstract "Treatment of patients with an esophageal source of chest pain remains a challenging problem. Although a variety of measures--including nitrates, anticholinergics, sedatives, calcium channel antagonists, esophageal dilation, and psychological reassurance--are available for the management of esophageal chest pain, none has emerged as the treatment of choice. Studies of nitrate preparations for the treatment of painful motility disorders are limited by a small number of patients and the lack of randomized, placebo-controlled investigations. The efficacy of anticholinergic drugs in hypercontractile esophageal motility disorders has not been reported. In the only prospective placebo-controlled trial using an anti-depressant, trazodone was superior to placebo in relieving symptoms in patients with a variety of esophageal motility disorders. Conflicting results have been described in placebo-controlled trials of the calcium channel antagonists nifedipine and diltiazem in patients with nutcracker esophagus or diffuse spasm. Information about the efficacy of verapamil and hydralazine is limited. Esophageal dilation has been useful in selected patients. For many patients, esophageal chest pain may be associated with gastroesophageal reflux. Treatment of these patients with nitrates, calcium channel antagonists, or anticholinergics may aggravate their reflux. The mechanisms of esophageal chest pain remain unknown. Recent studies have suggested that abnormal motility may not be the only factor associated with chest pain. An important number of patients have behavioral abnormalities, increased nociception, impaired coronary vasodilatory reserve, or a diffuse abnormality of smooth muscle. Research into rational therapy for chest pain patients should take into account the contribution of these other factors." @default.
• W1994459789 created "2016-06-24" @default.
• W1994459789 creator A5017452010 @default.
• W1994459789 creator A5030337980 @default.
• W1994459789 date "1992-05-01" @default.
• W1994459789 modified "2023-10-17" @default.
• W1994459789 title "Current Medical therapy for esophageal motility disorders" @default.
• W1994459789 cites W1552977327 @default.
• W1994459789 cites W1588019569 @default.
• W1994459789 cites W1605960867 @default.
• W1994459789 cites W1607360493 @default.
• W1994459789 cites W1791892063 @default.
• W1994459789 cites W1903090943 @default.
• W1994459789 cites W1929074801 @default.
• W1994459789 cites W1939061583 @default.
• W1994459789 cites W1939074796 @default.
• W1994459789 cites W1964131870 @default.
• W1994459789 cites W1968409528 @default.
• W1994459789 cites W1974962889 @default.
• W1994459789 cites W1982936434 @default.
• W1994459789 cites W1983129801 @default.
• W1994459789 cites W1986773965 @default.
• W1994459789 cites W2006121149 @default.
• W1994459789 cites W2006346614 @default.
• W1994459789 cites W2010851850 @default.
• W1994459789 cites W2012554857 @default.
• W1994459789 cites W2016554068 @default.
• W1994459789 cites W2021788599 @default.
• W1994459789 cites W2022544582 @default.
• W1994459789 cites W2026641019 @default.
• W1994459789 cites W2032107277 @default.
• W1994459789 cites W2036590129 @default.
• W1994459789 cites W2044454672 @default.
• W1994459789 cites W2050237468 @default.
• W1994459789 cites W2053977228 @default.
• W1994459789 cites W2061044682 @default.
• W1994459789 cites W2061519972 @default.
• W1994459789 cites W2067368985 @default.
• W1994459789 cites W2071666895 @default.
• W1994459789 cites W2077957969 @default.
• W1994459789 cites W2084906712 @default.
• W1994459789 cites W2094837823 @default.
• W1994459789 cites W2127794876 @default.
• W1994459789 cites W2129525289 @default.
• W1994459789 cites W2136994232 @default.
• W1994459789 cites W2174677354 @default.
• W1994459789 cites W2174825284 @default.
• W1994459789 cites W2179423939 @default.
• W1994459789 cites W2212072194 @default.
• W1994459789 cites W2325683452 @default.
• W1994459789 cites W23442131 @default.
• W1994459789 cites W2396670072 @default.
• W1994459789 cites W2400406382 @default.
• W1994459789 cites W2410246722 @default.
• W1994459789 cites W2414778462 @default.
• W1994459789 cites W2415421326 @default.
• W1994459789 cites W2415752067 @default.
• W1994459789 cites W2418657017 @default.
• W1994459789 cites W2420819978 @default.
• W1994459789 cites W2429422655 @default.
• W1994459789 cites W255240257 @default.
• W1994459789 cites W2799982273 @default.
• W1994459789 cites W62325350 @default.
• W1994459789 cites W6407037 @default.
• W1994459789 cites W93221082 @default.
• W1994459789 doi "https://doi.org/10.1016/0002-9343(92)80064-7" @default.
• W1994459789 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1595773" @default.
• W1994459789 hasPublicationYear "1992" @default.
• W1994459789 type Work @default.
• W1994459789 sameAs 1994459789 @default.
• W1994459789 citedByCount "22" @default.
• W1994459789 countsByYear W19944597892013 @default.
• W1994459789 countsByYear W19944597892014 @default.
• W1994459789 countsByYear W19944597892018 @default.
• W1994459789 countsByYear W19944597892023 @default.
• W1994459789 crossrefType "journal-article" @default.
• W1994459789 hasAuthorship W1994459789A5017452010 @default.
• W1994459789 hasAuthorship W1994459789A5030337980 @default.
• W1994459789 hasConcept C126322002 @default.
• W1994459789 hasConcept C142724271 @default.
• W1994459789 hasConcept C204787440 @default.
• W1994459789 hasConcept C27081682 @default.
• W1994459789 hasConcept C2776109754 @default.
• W1994459789 hasConcept C2776462128 @default.
• W1994459789 hasConcept C2776741139 @default.
• W1994459789 hasConcept C2777819096 @default.
• W1994459789 hasConcept C2778704086 @default.
• W1994459789 hasConcept C2779066535 @default.
• W1994459789 hasConcept C2779134260 @default.
• W1994459789 hasConcept C2779958274 @default.
• W1994459789 hasConcept C2780942740 @default.
• W1994459789 hasConcept C42219234 @default.
• W1994459789 hasConcept C43270747 @default.
• W1994459789 hasConcept C519063684 @default.
• W1994459789 hasConcept C71924100 @default.
• W1994459789 hasConceptScore W1994459789C126322002 @default.
• W1994459789 hasConceptScore W1994459789C142724271 @default.
• W1994459789 hasConceptScore W1994459789C204787440 @default.
• W1994459789 hasConceptScore W1994459789C27081682 @default.
• W1994459789 hasConceptScore W1994459789C2776109754 @default.

• next