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- W1994489757 abstract "The improvement of resistance to blast, a devastating fungal disease of rice, would support the sustainable production of one of the world's staple foods, yet the identification of genes for durable resistance in rice is a challenge owing to their complicated genetic control. Here we show that map-based cloning of Pi35 identifies multiple functional polymorphisms that allow effective control of the disease and that Pi35 is allelic to Pish, which mediates race-specific resistance to blast and encodes a protein containing a nucleotide-binding site (NBS) and leucine-rich repeats (LRRs). Analysis using Pish–Pi35 chimeric genes demonstrated that multiple functional polymorphisms cumulatively enhance resistance and that an amino acid residue in a LRR of Pi35 is strongly associated with the gene's mediation of quantitative but consistent resistance to pathogen isolates in Japan, in contrast to Pish, which mediates resistance to only a single isolate. Our results reinforce the substantial importance of mining allelic variation for crop breeding." @default.
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- W1994489757 date "2014-04-01" @default.
- W1994489757 modified "2023-10-16" @default.
- W1994489757 title "Multiple functional polymorphisms in a single disease resistance gene in rice enhance durable resistance to blast" @default.
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- W1994489757 doi "https://doi.org/10.1038/srep04550" @default.
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