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- W1994495458 abstract "High throughput screening is commonly defined as automatic testing of potential drug candidates at a rate in excess of 10,000 compounds per week. The aim of high throughput drug discovery is to test large compound collections for potentially active compounds ('hits') in order to allow further development of compounds for pre-clinical testing ('leads'). High throughput technology has emerged over the last few years as an important tool for drug discovery and lead optimisation. In this approach, the molecular diversity and range of biological properties displayed by secondary metabolites constitutes a challenge to combinatorial strategies for natural products synthesis and derivatization. This article reviews the approach of High throughput technique for the screening of natural products for drug discovery." @default.
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- W1994495458 date "2008-02-01" @default.
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- W1994495458 title "A review of high throughput technology for the screening of natural products" @default.
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- W1994495458 doi "https://doi.org/10.1016/j.biopha.2007.06.012" @default.
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