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- W1994499990 abstract "In a prospective double-blind comparison of contrast media for retrograde pancreatography, 85 consecutive patients undergoing endoscopic retrograde cholangio-pancreatography (ERCP) were randomised to receive either the non-ionic medium, iopamidol (Niopam) or the ionic medium, meglumine diatrizoate (Urografin). The quality of pancreatograms obtained was assessed blindly using a specially devised scoring system, and patients were observed for clinical and biochemical evidence of acute pancreatitis following ERCP. Pancreatogram scores were similar in the Niopam and Urografin groups. No patients developed clinical evidence of acute pancreatitis. Eighteen hours after ERCP median increments in serum amylase and lipase in the Niopam group were significantly lower and hyperamylasemia and hyperlipasemia significantly less frequent than in the Urografin group. Niopam may be a safer contrast medium than Urografin for retrograde pancreatography, particularly in patients in whom the risk of acute pancreatitis is high. However, in view of its relatively high cost, further direct clinical evidence of reduced toxicity is required before Niopam can be recommended for routine use at ERCP." @default.
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- W1994499990 date "1988-09-01" @default.
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- W1994499990 title "Iopamidol as Contrast Medium in Endoscopic Retrograde Pancreatography: A Prospective Randomised Comparison with Diatrizoate" @default.
- W1994499990 doi "https://doi.org/10.1055/s-2007-1013022" @default.
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